Cell Biology Antibodies 3
Anti-CFHR3 Antibody (CAB13400)
- SKU:
- CAB13400
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-CFHR3 Antibody |
Antibody SKU: | CAB13400 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | AVPC LRKC YFPY LENG YNQN YGRK FVQG NSTE VACH PGYG LPKA QTTV TCTE KGWS PTPR CIRV RTCS KSDI EIEN GFIS ESSS IYIL NKEI QYKC KPGY ATAD GNSS GSIT CLQN GWSA Q |
Gene ID: | 10878 |
Uniprot: | Q02985 |
Cellular Location: | Secreted |
Calculated MW: | 30kDa/37kDa |
Observed MW: |
Synonyms: | CFHR3, CFHL3, DOWN16, FHR-3, FHR3, HLF4 |
Background: | The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Might be involved in complement regulation. |
NCBI Summary: | The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | Q02985 |
NCBI GenInfo Identifier: | 262231791 |
NCBI Gene ID: | 10878 |
NCBI Accession: | NP_001160096.1 |
UniProt Related Accession: | Q02985 |
Molecular Weight: | |
NCBI Full Name: | complement factor H-related protein 3 isoform 2 |
NCBI Synonym Full Names: | complement factor H related 3 |
NCBI Official Symbol: | CFHR3 |
NCBI Official Synonym Symbols: | FHR3; HLF4; CFHL3; FHR-3; DOWN16 |
NCBI Protein Information: | complement factor H-related protein 3 |
UniProt Protein Name: | Complement factor H-related protein 3 |
UniProt Synonym Protein Names: | DOWN16; H factor-like protein 3 |
UniProt Gene Name: | CFHR3 |
Immunofluorescence analysis of A549 cells using CFHR3 antibody (CAB13400). Blue: DAPI for nuclear staining. |
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