Cell Biology Antibodies 3
Anti-CFHR3 Antibody (CAB13400)
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- SKU:
- CAB13400
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CFHR3 Antibody |
| Antibody SKU: | CAB13400 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AVPC LRKC YFPY LENG YNQN YGRK FVQG NSTE VACH PGYG LPKA QTTV TCTE KGWS PTPR CIRV RTCS KSDI EIEN GFIS ESSS IYIL NKEI QYKC KPGY ATAD GNSS GSIT CLQN GWSA Q |
| Gene ID: | 10878 |
| Uniprot: | Q02985 |
| Cellular Location: | Secreted |
| Calculated MW: | 30kDa/37kDa |
| Observed MW: |
| Synonyms: | CFHR3, CFHL3, DOWN16, FHR-3, FHR3, HLF4 |
| Background: | The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Might be involved in complement regulation. |
| NCBI Summary: | The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q02985 |
| NCBI GenInfo Identifier: | 262231791 |
| NCBI Gene ID: | 10878 |
| NCBI Accession: | NP_001160096.1 |
| UniProt Related Accession: | Q02985 |
| Molecular Weight: | |
| NCBI Full Name: | complement factor H-related protein 3 isoform 2 |
| NCBI Synonym Full Names: | complement factor H related 3 |
| NCBI Official Symbol: | CFHR3 |
| NCBI Official Synonym Symbols: | FHR3; HLF4; CFHL3; FHR-3; DOWN16 |
| NCBI Protein Information: | complement factor H-related protein 3 |
| UniProt Protein Name: | Complement factor H-related protein 3 |
| UniProt Synonym Protein Names: | DOWN16; H factor-like protein 3 |
| UniProt Gene Name: | CFHR3 |
 | Immunofluorescence analysis of A549 cells using CFHR3 antibody (CAB13400). Blue: DAPI for nuclear staining. |
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