Cell Biology Antibodies 7
Anti-CFAP53 Antibody (CAB16607)
(No reviews yet)
Write a Review
- SKU:
- CAB16607
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CFAP53 Antibody |
| Antibody SKU: | CAB16607 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CFAP53 (NP_659457.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse testis, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CFAP53 (NP_659457.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MYSQ RFGT VQRE VKGP TPKV VIVR SKPP KGQG AEHH LERI RRSH QKHN AILA SIKS SERD RLKA EWDQ HNDC KILD SLVR ARIK DAVQ GFII NIEE RRNK LREL LALE ENEY FTEM QLKK ETIE EKKD RMRE KTKL LKEK NEKE RQDF VAEK LDQQ FRER CEEL RVEL LSIH QKKV CEER KAQI AFNE ELSR QKLV EEQM FSKL WEED RLAK EKRE AQEA RRQK ELME NTRL GLNA QITS IKAQ RQAT QLLK EEEA RLVE SNNA QIKH ENEQ DMLK KQKA KQET RTIL QKAL QERI EHIQ |
| Gene ID: | 220136 |
| Uniprot: | Q96M91 |
| Cellular Location: | Cell projection, cilium |
| Calculated MW: | 61kDa |
| Observed MW: | 62kDa |
| Synonyms: | CFAP53, CCDC11, HTX6 |
| Background: | This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning. |
| UniProt Protein Function: | CCDC11: Defects in CCDC11 are the cause of heterotaxy, visceral, type 6, autosomal (HTX6). A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. HTX6 clinical features are situs inversus totalis and severe complex cardiac malformations including unbalanced atrioventricular canal defects, transposition of the great arteries with severe pulmonary stenosis, right aortic arch, abnormal systemic venous return and total anomalous pulmonary venous drainage. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 18q21.1 Cellular Component: cilium Disease: Heterotaxy, Visceral, 6, Autosomal |
| NCBI Summary: | This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning. [provided by RefSeq, Aug 2015] |
| UniProt Code: | Q96M91 |
| NCBI GenInfo Identifier: | 118572626 |
| NCBI Gene ID: | 220136 |
| NCBI Accession: | Q96M91.2 |
| UniProt Secondary Accession: | Q96M91,B4DXT1, |
| UniProt Related Accession: | Q96M91 |
| Molecular Weight: | 61,835 Da |
| NCBI Full Name: | Coiled-coil domain-containing protein 11 |
| NCBI Synonym Full Names: | cilia and flagella associated protein 53 |
| NCBI Official Symbol: | CFAP53 |
| NCBI Official Synonym Symbols: | HTX6; CCDC11 |
| NCBI Protein Information: | coiled-coil domain-containing protein 11; coiled-coil domain containing 11 |
| UniProt Protein Name: | Coiled-coil domain-containing protein 11 |
| Protein Family: | Cilia- and flagella-associated protein |
| UniProt Gene Name: | CCDC11 |
| UniProt Entry Name: | CCD11_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CFAP53 antibody (CAB16607) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunofluorescence analysis of HeLa cells using CFAP53 Rabbit pAb (CAB16607) at dilution of 1:100. Blue: DAPI for nuclear staining. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA Kit
OverviewProduct Name:Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA KitProduct Code:AEFI00360Size:96TAlias:a