Cell Biology Antibodies 18
Anti-CERS2 Antibody (CAB18236)
- SKU:
- CAB18236
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-CERS2 Antibody |
Antibody SKU: | CAB18236 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human CERS2. |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: |
Immunogen: | Recombinant protein of human CERS2. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 29956 |
Uniprot: | Q96G23 |
Cellular Location: | |
Calculated MW: | 45kDa |
Observed MW: | Refer to figures |
Synonyms: | CERS2, L3, LASS2, SP260, TMSG1 |
Background: | This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. |
UniProt Protein Function: | LASS2: Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis. |
UniProt Protein Details: | Protein type:DNA-binding; Membrane protein, integral; Transferase; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane; nuclear membrane Molecular Function:protein binding; sphingosine N-acyltransferase activity Biological Process: ceramide biosynthetic process; negative regulation of axon regeneration; sphingolipid biosynthetic process |
NCBI Summary: | This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96G23 |
NCBI GenInfo Identifier: | 51316514 |
NCBI Gene ID: | 29956 |
NCBI Accession: | Q96G23.1 |
UniProt Secondary Accession: | Q96G23,Q5SZE5, Q9HD96, Q9NW79, D3DV06, |
UniProt Related Accession: | Q96G23 |
Molecular Weight: | 44,876 Da |
NCBI Full Name: | Ceramide synthase 2 |
NCBI Synonym Full Names: | ceramide synthase 2 |
NCBI Official Symbol: | CERS2 |
NCBI Official Synonym Symbols: | L3; LASS2; SP260; TMSG1 |
NCBI Protein Information: | ceramide synthase 2 |
UniProt Protein Name: | Ceramide synthase 2 |
UniProt Synonym Protein Names: | LAG1 longevity assurance homolog 2; SP260; Tumor metastasis-suppressor gene 1 protein |
Protein Family: | Ceramide synthase |
UniProt Gene Name: | CERS2 |
UniProt Entry Name: | CERS2_HUMAN |