Cell Biology Antibodies 11
Anti-CEP120 Antibody (CAB8004)
- SKU:
- CAB8004
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | CEP120 Rabbit Polyclonal Antibody |
Antibody SKU: | CAB8004 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | A-549, HeLa, Mouse brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MVSK SDQL LIVV SILE GRHF PKRP KHML VVEA KFDG EQLA TDPV DHTD QPEF ATEL AWEI DRKA LHQH RLQR TPIK LQCF ALDP VTSA KETI GYIV LDLR TAQE TKQA PKWY QLLS NKYT KFKS EIQI SIAL ETDT KPPV DSFK AKGA PPRD GKVP AILA GLDP RDIV AVLN EEGG YHQI GPAE YCTD SFIM SVTI AFAT QLEQ LIPC TMKL PERQ PEFF FYYS LLGN DVTN EPFN DLIN PNFE PERA SVRI RSSV EILR VYLA LQSK LQ |
Gene ID: | 153241 |
Uniprot: | Q8N960 |
Cellular Location: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center |
Calculated MW: | 42kDa/109kDa/112kDa |
Observed MW: | 120kDa |
Synonyms: | CEP120, CCDC100, SRTD13 |
Background: | This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis. |
NCBI Summary: | This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q8N960 |
NCBI GenInfo Identifier: | 205696377 |
NCBI Gene ID: | 153241 |
NCBI Accession: | Q8N960.2 |
UniProt Secondary Accession: | Q8N960,Q6AI52, Q6AW89, Q8IWB5, Q8N9Y0, Q8NDE8, |
UniProt Related Accession: | Q8N960 |
Molecular Weight: | 42,705 Da |
NCBI Full Name: | Centrosomal protein of 120 kDa |
NCBI Synonym Full Names: | centrosomal protein 120 |
NCBI Official Symbol: | CEP120 |
NCBI Official Synonym Symbols: | JBTS31; SRTD13; CCDC100 |
NCBI Protein Information: | centrosomal protein of 120 kDa |
UniProt Protein Name: | Centrosomal protein of 120 kDa |
UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 100 |
Protein Family: | Centrosomal protein |
UniProt Gene Name: | CEP120 |
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