Cell Biology Antibodies 18
Anti-CELSR2 Antibody (CAB18359)
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- SKU:
- CAB18359
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CELSR2 Antibody |
| Antibody SKU: | CAB18359 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human CELSR2. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human CELSR2. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1952 |
| Uniprot: | Q9HCU4 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | ADGRC2, CDHF10, EGFL2, Flamingo1, MEGF3, CELSR2 |
| Background: |
| UniProt Protein Function: | CELSR2: Receptor that may have an important role in cell/cell signaling during nervous system formation. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, multi-pass; Cell development/differentiation; Membrane protein, integral; GPCR, family 2 Chromosomal Location of Human Ortholog: 1p21 Cellular Component: cytoplasm; integral to membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; calcium ion binding Biological Process: G-protein coupled receptor protein signaling pathway; cerebrospinal fluid secretion; regulation of protein localization; Wnt receptor signaling pathway; regulation of cell-cell adhesion; regulation of transcription, DNA-dependent; neural plate anterioposterior pattern formation; ventricular system development; dendrite morphogenesis; neuron migration; cilium biogenesis; homophilic cell adhesion |
| NCBI Summary: | The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HCU4 |
| NCBI GenInfo Identifier: | 22095550 |
| NCBI Gene ID: | 1952 |
| NCBI Accession: | Q9HCU4.1 |
| UniProt Secondary Accession: | Q9HCU4,Q5T2Y7, Q92566, |
| UniProt Related Accession: | Q9HCU4 |
| Molecular Weight: | 317,453 Da |
| NCBI Full Name: | Cadherin EGF LAG seven-pass G-type receptor 2 |
| NCBI Synonym Full Names: | cadherin, EGF LAG seven-pass G-type receptor 2 |
| NCBI Official Symbol: | CELSR2 |
| NCBI Official Synonym Symbols: | EGFL2; MEGF3; CDHF10; Flamingo1 |
| NCBI Protein Information: | cadherin EGF LAG seven-pass G-type receptor 2; EGF-like protein 2; flamingo homolog 3; cadherin family member 10; EGF-like-domain, multiple 2; epidermal growth factor-like 2; multiple EGF-like domains protein 3; epidermal growth factor-like protein 2; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) |
| UniProt Protein Name: | Cadherin EGF LAG seven-pass G-type receptor 2 |
| UniProt Synonym Protein Names: | Cadherin family member 10; Epidermal growth factor-like protein 2; EGF-like protein 2; Flamingo homolog 3; Multiple epidermal growth factor-like domains protein 3; Multiple EGF-like domains protein 3 |
| Protein Family: | Cadherin EGF LAG seven-pass G-type receptor |
| UniProt Gene Name: | CELSR2 |
| UniProt Entry Name: | CELR2_HUMAN |
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