Epigenetics & Nuclear Signaling Antibodies 4

Anti-CEBPE Antibody (CAB8047)

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SKU:
CAB8047
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:CEBPE Rabbit Polyclonal Antibody
Antibody SKU:CAB8047
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CEBPE (NP_001796.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:NCI-H460, Mouse spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CEBPE (NP_001796.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSHG TYYE CEPR GGQQ PLEF SGGR AGPG ELGD MCEH EASI DLSA YIES GEEQ LLSD LFAV KPAP EARG LKGP GTPA FPHY LPPD PRPF AYPP HTFG PDRK ALGP GIYS SPGS YDPR AVAV KEEP RGPE GSRA ASRG SYNP LQYQ VAHC GQTA MHLP PTLA APGQ PLRV LKAP LATA APPC SPLL KAPS PA
Gene ID:1053
Uniprot:Q15744
Cellular Location:Nucleus
Calculated MW:30kDa
Observed MW:35kDa
Synonyms:CEBPE, C/EBP-epsilon, CRP1
Background:The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined.
UniProt Protein Function:C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm

Biological Process: defense response; positive regulation of transcription from RNA polymerase II promoter

Disease: Specific Granule Deficiency

NCBI Summary:The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q15744
NCBI GenInfo Identifier:62512175
NCBI Gene ID:1053
NCBI Accession:Q15744.2
UniProt Secondary Accession:Q15744,Q15745, Q8IYI2, Q99803,
UniProt Related Accession:Q15744
Molecular Weight:30,603 Da
NCBI Full Name:CCAAT/enhancer-binding protein epsilon
NCBI Synonym Full Names:CCAAT/enhancer binding protein epsilon
NCBI Official Symbol:CEBPE  
NCBI Official Synonym Symbols:CRP1; C/EBP-epsilon  
NCBI Protein Information:CCAAT/enhancer-binding protein epsilon
UniProt Protein Name:CCAAT/enhancer-binding protein epsilon
Protein Family:CCAAT/enhancer-binding protein
UniProt Gene Name:CEBPE  
UniProt Entry Name:CEBPE_HUMAN
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