Epigenetics & Nuclear Signaling Antibodies 2

Anti-CEBPD Antibody (CAB15261)

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SKU:
CAB15261
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-CEBPD Antibody
Antibody SKU:CAB15261
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human CEBPD (NP_005186.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human CEBPD (NP_005186.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSAA LFSL DGPA RGAP WPAE PAPF YEPG RAGK PGRG AEPG ALGE PGAA APAM YDDE SAID FSAY IDSM AAVP TLEL CHDE LFAD LFNS NHKA GGAG PLEL LPGG PARP LGPG PAAP RLLK REPD WGDG DAPG SLLP AQVA ACAQ TVVS LAAA GQPT PPTS PEPP RSSP RQTP APGP AREK SAGK RGPD RGSP EYRQ RRER NNIA VRKS RDKA KRRN QEMQ QKLV ELSA ENEK LHQR VEQL TRDL AGLR QFFK QLPS PPFL PAAG TADC R
Gene ID:1052
Uniprot:P49716
Cellular Location:Nucleus
Calculated MW:28kDa
Observed MW:28kDa
Synonyms:CEBPD, C/EBP-delta, CELF, CRP3, NF-IL6-beta
Background:The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11.
UniProt Protein Function:C/EBP-delta: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1. Interacts with PRDM16. Belongs to the bZIP family. C/EBP subfamily.
UniProt Protein Details:

Protein type:DNA-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8p11.2-p11.1

Cellular Component: nucleus

Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter

NCBI Summary:The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]
UniProt Code:P49716
NCBI GenInfo Identifier:160332350
NCBI Gene ID:1052
NCBI Accession:P49716.2
UniProt Secondary Accession:P49716,Q03484,
UniProt Related Accession:P49716
Molecular Weight:269
NCBI Full Name:CCAAT/enhancer-binding protein delta
NCBI Synonym Full Names:CCAAT/enhancer binding protein (C/EBP), delta
NCBI Official Symbol:CEBPD  
NCBI Official Synonym Symbols:CELF; CRP3; C/EBP-delta; NF-IL6-beta  
NCBI Protein Information:CCAAT/enhancer-binding protein delta; c/EBP delta; nuclear factor NF-IL6-beta
UniProt Protein Name:CCAAT/enhancer-binding protein delta
UniProt Synonym Protein Names:Nuclear factor NF-IL6-beta; NF-IL6-beta
Protein Family:CCAAT/enhancer-binding protein
UniProt Gene Name:CEBPD  
UniProt Entry Name:CEBPD_HUMAN
Anti-CEBPD Antibody (CAB15261)Western blot analysis of extracts of mouse lung, using CEBPD antibody (CAB15261) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90S.
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