Cell Biology Antibodies 11
Anti-CEACAM7 Antibody (CAB8112)
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- SKU:
- CAB8112
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | CEACAM7 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8112 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-242 of human CEACAM7 (NP_008821.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-242 of human CEACAM7 (NP_008821.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TNID VVPF NVAE GKEV LLVV HNES QNLY GYNW YKGE RVHA NYRI IGYV KNIS QENA PGPA HNGR ETIY PNGT LLIQ NVTH NDAG IYTL HVIK ENLV NEEV TRQF YVFS EPPK PSIT SNNF NPVE NKDI VVLT CQPE TQNT TYLW WVNN QSLL VSPR LLLS TDNR TLVL LSAT KNDI GPYE CEIQ NPVG ASRS DPVT LNVR YESV QAS |
| Gene ID: | 1087 |
| Uniprot: | Q14002 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
| Calculated MW: | 19kDa/29kDa |
| Observed MW: | 29kDa |
| Synonyms: | CEACAM7, CGM2 |
| Background: | This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | CEACAM7: Belongs to the immunoglobulin superfamily. CEA family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: plasma membrane; integral to membrane |
| NCBI Summary: | This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
| UniProt Code: | Q14002 |
| NCBI GenInfo Identifier: | 5901930 |
| NCBI Gene ID: | 1087 |
| NCBI Accession: | NP_008821.1 |
| UniProt Secondary Accession: | Q14002,O15148, O15149, Q0VAC1, Q13983, Q9UPJ2, A8K848 |
| UniProt Related Accession: | Q14002 |
| Molecular Weight: | 19,031 Da |
| NCBI Full Name: | carcinoembryonic antigen-related cell adhesion molecule 7 |
| NCBI Synonym Full Names: | carcinoembryonic antigen related cell adhesion molecule 7 |
| NCBI Official Symbol: | CEACAM7 |
| NCBI Official Synonym Symbols: | CGM2 |
| NCBI Protein Information: | carcinoembryonic antigen-related cell adhesion molecule 7 |
| UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 7 |
| UniProt Synonym Protein Names: | Carcinoembryonic antigen CGM2 |
| Protein Family: | Carcinoembryonic antigen-related cell adhesion molecule |
| UniProt Gene Name: | CEACAM7 |
| UniProt Entry Name: | CEAM7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CEACAM7 antibody (CAB8112) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using CEACAM7 antibody (CAB8112) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using CEACAM7 antibody (CAB8112) at dilution of 1:100 (40x lens). |
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