Name: Anti-CDKN2AIP Antibody (CAB3233)
Brand: Cell Biology Antibodies 8
SKU: CAB3233
Availability: OutOfStock

Antibody Name:	Anti-CDKN2AIP Antibody
Antibody SKU:	CAB3233
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:1000 IHC 1:50 - 1:100
Reactivity:	Human, Mouse, Rat
Positive Samples:	SKOV3, Mouse thymus, Rat thymus

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MAQE VSEY LSQN PRVA AWVE ALRC DGET DKHW RHRR DFLL RNAG DLAP AGGA ASAS TDEA ADAE SGTR NRQL QQLI SFSM AWAN HVFL GCRY PQKV MDKI LSMA EGIK VTDA PTYT TRDE LVAK VKKR GISS SNEG VEEP SKKR VIEG KNSS AVEQ DHAK TSAK TERA SAQQ ENSS TCIG SAIK SESG NSAR SSGI SSQN SSTS DGDR SVSS QSSS SVSS
Gene ID:	55602
Uniprot:	Q9NXV6
Cellular Location:	Nucleus, nucleoplasm
Calculated MW:	61kDa
Observed MW:	65kDa

Synonyms:	CDKN2AIP, CARF
Background:	The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene.

UniProt Protein Function:	CDKN2AIP: co-localizes and interacts with p14ARF in the nucleolus. Co-regulated with ARF and cooperates with it in activating p53.
UniProt Protein Details:	Protein type:Unknown function Chromosomal Location of Human Ortholog: 4q35.1 Cellular Component: nucleoplasm; granular component; cytoplasm; nucleolus; nucleus Molecular Function:protein binding; RNA binding; p53 binding Biological Process: positive regulation of signal transduction; regulation of protein stability; negative regulation of cell growth; response to DNA damage stimulus; positive regulation of cell growth
NCBI Summary:	The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
UniProt Code:	Q9NXV6
NCBI GenInfo Identifier:	327478591
NCBI Gene ID:	55602
NCBI Accession:	Q9NXV6.3
UniProt Related Accession:	Q9NXV6
Molecular Weight:
NCBI Full Name:	CDKN2A-interacting protein
NCBI Synonym Full Names:	CDKN2A interacting protein
NCBI Official Symbol:	CDKN2AIP
NCBI Official Synonym Symbols:	CARF
NCBI Protein Information:	CDKN2A-interacting protein
UniProt Protein Name:	CDKN2A-interacting protein
UniProt Synonym Protein Names:	Collaborator of ARF
Protein Family:	Calcium-responsive transcription factor
UniProt Gene Name:	CDKN2AIP
UniProt Entry Name:	CARF_HUMAN

Western blot analysis of extracts of various cell lines, using CDKN2AIP antibody (CAB3233) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.

Antibodies

CDKN2AIP Antibody (PACO08347)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)