Immunology Antibodies 2
Anti-CDK5RAP3 Antibody (CAB5000)
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- SKU:
- CAB5000
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDK5RAP3
- Synonyms:
- C53
- Synonyms:
- HSF-27
- Synonyms:
- IC53
- Synonyms:
- LZAP
- Synonyms:
- MST016
- Synonyms:
- OK/SW-cl.114
- Synonyms:
- PP1553
- Research Area:
- Immunology
Description
| Product Name: | CDK5RAP3 Rabbit pAb |
| Product Code: | CAB5000 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CDK5RAP3, C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDK5RAP3 (NP_788276.1). |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, 293T, LO2, A549, HT-29, Mouse brain, Mouse kidney, Mouse liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDK5RAP3 (NP_788276.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEDH QHVP IDIQ TSKL LDWL VDRR HCSL KWQS LVLT IREK INAA IQDM PESE EIAQ LLSG SYIH YFHC LRIL DLLK GTEA STKN IFGR YSSQ RMKD WQEI IALY EKDN TYLV ELSS LLVR NVNY EIPS LKKQ IAKC QQLQ QEYS RKEE ECQA GAAE MREQ FYHS CKQY GITG ENVR GELL ALVK DLPS QLAE IGAA AQQS LGEA IDVY QASV GFVC ESPT EQVL PMLR FVQK RGNS TVYE WRTG TEPS VVER PHLE ELPE QVAE DAID WGDF GVEA VSEG TDSG ISAE AAGI DWGI FPES |
| Gene ID: | 80279 |
| Uniprot: | Q96JB5 |
| Cellular Location: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center |
| Calculated MW: | 31kDa/46kDa/56kDa/59kDa |
| Observed MW: | 69kDa |
| UniProt Protein Function: | CDK5RAP3: Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1. Belongs to the CDK5RAP3 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 17q21.32 Cellular Component: protein complex; membrane; cytoplasm; nucleolus; endomembrane system; nucleus Molecular Function:cyclin binding; protein binding; protein kinase binding Biological Process: cell proliferation; regulation of neuron differentiation; positive regulation of protein ubiquitination; inhibition of NF-kappaB transcription factor; regulation of mitotic cell cycle; positive regulation of transcription from RNA polymerase II promoter; brain development; regulation of cyclin-dependent protein kinase activity |
| NCBI Summary: | This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013] |
| UniProt Code: | Q96JB5 |
| NCBI GenInfo Identifier: | 32129444 |
| NCBI Gene ID: | 80279 |
| NCBI Accession: | Q96JB5.2 |
| UniProt Secondary Accession: | Q96JB5,Q53FA2, Q9H3F8, Q9H8G0, Q9HBR9, B7Z6N4, D3DTU1 D3DTU2, F5H3I5, |
| UniProt Related Accession: | Q96JB5 |
| Molecular Weight: | 506 |
| NCBI Full Name: | CDK5 regulatory subunit-associated protein 3 |
| NCBI Synonym Full Names: | CDK5 regulatory subunit associated protein 3 |
| NCBI Official Symbol: | CDK5RAP3 |
| NCBI Official Synonym Symbols: | C53; IC53; LZAP; HSF-27; MST016; PP1553; OK/SW-cl.114 |
| NCBI Protein Information: | CDK5 regulatory subunit-associated protein 3; CDK5 regulatory subunit associated protein IC53-2; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARFbinding protein |
| UniProt Protein Name: | CDK5 regulatory subunit-associated protein 3 |
| UniProt Synonym Protein Names: | CDK5 activator-binding protein C53; Protein HSF-27 |
| Protein Family: | CDK5RAP3-like protein |
| UniProt Gene Name: | CDK5RAP3 |
| UniProt Entry Name: | CK5P3_HUMAN |
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