Cell Biology Antibodies 13
Anti-CDK5R2 Antibody (CAB17583)
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- SKU:
- CAB17583
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CDK5R2 Antibody |
| Antibody SKU: | CAB17583 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-310 of human CDK5R2 (NP_003927.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-310 of human CDK5R2 (NP_003927.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PGGS PRRV IVQA STGE LLRC LGDF VCRR CYRL KELS PGEL VGWF RGVD RSLL LQGW QDQA FITP ANLV FVYL LCRE SLRG DELA SAAE LQAA FLTC LYLA YSYM GNEI SYPL KPFL VEPD KERF WQRC LRLI QRLS PQML R |
| Gene ID: | 8941 |
| Uniprot: | Q13319 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 45kDa |
 | Western blot - CDK5R2 Polyclonal Antibody (CAB17583) |
| Synonyms: | NCK5AI, P39, p39nck5ai, CDK5R2 |
| Background: | The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | CDK5R2: Activator of CDK5/TPKII. Heterodimer of a catalytic subunit and a regulatory subunit. Brain and neuron specific. Belongs to the cyclin-dependent kinase 5 activator family. |
| UniProt Protein Details: | Protein type:Protein kinase, regulatory subunit Chromosomal Location of Human Ortholog: 2q35 Cellular Component: cyclin-dependent protein kinase 5 activator complex; cytoplasm; plasma membrane Molecular Function:cyclin-dependent protein kinase 5 activator activity; lipid binding Biological Process: superior olivary nucleus maturation; positive regulation of calcium ion-dependent exocytosis; hippocampus development; neuron migration; cerebellum development; regulation of cyclin-dependent protein kinase activity; layer formation in the cerebral cortex |
| NCBI Summary: | The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13319 |
| NCBI GenInfo Identifier: | 4502739 |
| NCBI Gene ID: | 8941 |
| NCBI Accession: | NP_003927.1 |
| UniProt Related Accession: | Q13319 |
| Molecular Weight: | |
| NCBI Full Name: | cyclin-dependent kinase 5 activator 2 |
| NCBI Synonym Full Names: | cyclin dependent kinase 5 regulatory subunit 2 |
| NCBI Official Symbol: | CDK5R2 |
| NCBI Official Synonym Symbols: | P39; NCK5AI; p39nck5ai |
| NCBI Protein Information: | cyclin-dependent kinase 5 activator 2 |
| UniProt Protein Name: | Cyclin-dependent kinase 5 activator 2 |
| UniProt Synonym Protein Names: | Cyclin-dependent kinase 5 regulatory subunit 2; p39; p39I |
| UniProt Gene Name: | CDK5R2 |
| UniProt Entry Name: | CD5R2_HUMAN |
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