Cell Cycle Antibodies 1
Anti-CDK20 Antibody (CAB11599)
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- SKU:
- CAB11599
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-CDK20 Antibody |
| Antibody SKU: | CAB11599 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human CDK20 (NP_001164110.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, U-87MG, HepG2, Mouse heart, Mouse eye |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human CDK20 (NP_001164110.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDQY CILG RIGE GAHG IVFK AKHV ETGE IVAL KKVA LRRL EDGF PNQA LREI KALQ EMED NQYV VQLK AVFP HGGG FVLA FEFM LSDL AEVV RHAQ RPLA QAQV KSYL QMLL KGVA FCHA NNIV HRDL KPAN LLIS ASGQ LKIA DFGL ARVF SPDG SRLY THQV ATRS VGCI MGEL LNGS PLFP GKND IEQL CYVL RILG TPNP QVWP ELTE LPDY NKIS FKEQ VPMP LEEV LPDV SPQA LDLL GQFL LYPP HQRI AASK LPCL PIHL SCRF LSV |
| Gene ID: | 23552 |
| Uniprot: | Q8IZL9 |
| Cellular Location: | Cell projection, Cytoplasm, Nucleus, cilium |
| Calculated MW: | 27kDa/30kDa/36kDa/37kDa/38kDa |
| Observed MW: | 38kDa |
| Synonyms: | CDK20, CCRK, CDCH, P42, PNQALRE |
| Background: | The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| UniProt Protein Function: | CDK20: cyclin-dependent protein kinase H. A CMGC kinase of the CDK family. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Protein kinase, CMGC; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Motility/polarity/chemotaxis; CMGC group; CDK family; CCRK subfamily; CDK/CCRK subfamily Chromosomal Location of Human Ortholog: 9q22.1 Cellular Component: cytoplasm; nucleus; cilium Molecular Function:protein binding; cyclin-dependent protein kinase activity; ATP binding Biological Process: regulation of cell cycle; cell division; multicellular organismal development; cell cycle; protein amino acid phosphorylation |
| NCBI Summary: | The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q8IZL9 |
| NCBI GenInfo Identifier: | 74759739 |
| NCBI Gene ID: | 23552 |
| NCBI Accession: | Q8IZL9.1 |
| UniProt Secondary Accession: | Q8IZL9,O95137, Q5EDC4, Q5VYW1, Q9BUF4, A2A389, A2A390 B4DQX1, |
| UniProt Related Accession: | Q8IZL9 |
| Molecular Weight: | 36,113 Da |
| NCBI Full Name: | Cyclin-dependent kinase 20 |
| NCBI Synonym Full Names: | cyclin-dependent kinase 20 |
| NCBI Official Symbol: | CDK20 |
| NCBI Official Synonym Symbols: | P42; CCRK; CDCH; PNQALRE |
| NCBI Protein Information: | cyclin-dependent kinase 20; CAK-kinase p42; CDK-activating kinase p42; cell cycle-related kinase; cell division protein kinase 20; cyclin-dependent protein kinase H; cyclin-kinase-activating kinase p42 |
| UniProt Protein Name: | Cyclin-dependent kinase 20 |
| UniProt Synonym Protein Names: | CDK-activating kinase p42; CAK-kinase p42; Cell cycle-related kinase; Cell division protein kinase 20; Cyclin-dependent protein kinase H; Cyclin-kinase-activating kinase p42 |
| UniProt Gene Name: | CDK20 |
| UniProt Entry Name: | CDK20_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CDK20 antibody (CAB11599) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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