Cell Biology Antibodies 6

Anti-CDK19 Antibody (CAB16109)

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SKU:
CAB16109
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CDK19 Antibody
Antibody SKU:CAB16109
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CDK19 (XP_005266928.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:DU145, U-87MG, A-549, HeLa
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CDK19 (XP_005266928.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QQQN QHQQ PTAP PQQA AAPP QAPP PQQN STQT NGTA GGAG AGVG GTGA GLQH SQDS SLNQ VPPN KKPR LGPS GANS GGPV MPSD YQHS SSRL NYQS SVQG S
Gene ID:23097
Uniprot:Q9BWU1
Cellular Location:
Calculated MW:49kDa/56kDa
Observed MW:57kDa
Synonyms:CDK19, CDC2L6, CDK11, bA346C16.3
Background:This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
UniProt Protein Function:CDK19: a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; EC 2.7.11.22; Cell cycle regulation; Kinase, protein; CMGC group; CDK family; CDK8 subfamily

Chromosomal Location of Human Ortholog: 6q21

NCBI Summary:This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
UniProt Code:Q9BWU1
NCBI GenInfo Identifier:60391917
NCBI Gene ID:23097
NCBI Accession:Q9BWU1.1
UniProt Secondary Accession:Q9BWU1,Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2,
UniProt Related Accession:Q9BWU1
Molecular Weight:49,870 Da
NCBI Full Name:Cyclin-dependent kinase 19
NCBI Synonym Full Names:cyclin dependent kinase 19
NCBI Official Symbol:CDK19  
NCBI Official Synonym Symbols:CDK11; CDC2L6; bA346C16.3  
NCBI Protein Information:cyclin-dependent kinase 19
UniProt Protein Name:Cyclin-dependent kinase 19
UniProt Synonym Protein Names:CDC2-related protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; Cyclin-dependent kinase 11; Death-preventing kinase
Protein Family:Cyclin-dependent kinase
UniProt Gene Name:CDK19  
UniProt Entry Name:CDK19_HUMAN
Anti-CDK19 Antibody (CAB16109)Western blot analysis of extracts of various cell lines, using CDK19 antibody (CAB16109) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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