Cell Biology Antibodies 6
Anti-CDK19 Antibody (CAB16109)
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- SKU:
- CAB16109
Description
| Antibody Name: | Anti-CDK19 Antibody |
| Antibody SKU: | CAB16109 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CDK19 (XP_005266928.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | DU145, U-87MG, A-549, HeLa |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CDK19 (XP_005266928.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QQQN QHQQ PTAP PQQA AAPP QAPP PQQN STQT NGTA GGAG AGVG GTGA GLQH SQDS SLNQ VPPN KKPR LGPS GANS GGPV MPSD YQHS SSRL NYQS SVQG S |
| Gene ID: | 23097 |
| Uniprot: | Q9BWU1 |
| Cellular Location: | |
| Calculated MW: | 49kDa/56kDa |
| Observed MW: | 57kDa |
| Synonyms: | CDK19, CDC2L6, CDK11, bA346C16.3 |
| Background: | This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| UniProt Protein Function: | CDK19: a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; EC 2.7.11.22; Cell cycle regulation; Kinase, protein; CMGC group; CDK family; CDK8 subfamily Chromosomal Location of Human Ortholog: 6q21 |
| NCBI Summary: | This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9BWU1 |
| NCBI GenInfo Identifier: | 60391917 |
| NCBI Gene ID: | 23097 |
| NCBI Accession: | Q9BWU1.1 |
| UniProt Secondary Accession: | Q9BWU1,Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2, |
| UniProt Related Accession: | Q9BWU1 |
| Molecular Weight: | 49,870 Da |
| NCBI Full Name: | Cyclin-dependent kinase 19 |
| NCBI Synonym Full Names: | cyclin dependent kinase 19 |
| NCBI Official Symbol: | CDK19 |
| NCBI Official Synonym Symbols: | CDK11; CDC2L6; bA346C16.3 |
| NCBI Protein Information: | cyclin-dependent kinase 19 |
| UniProt Protein Name: | Cyclin-dependent kinase 19 |
| UniProt Synonym Protein Names: | CDC2-related protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; Cyclin-dependent kinase 11; Death-preventing kinase |
| Protein Family: | Cyclin-dependent kinase |
| UniProt Gene Name: | CDK19 |
| UniProt Entry Name: | CDK19_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CDK19 antibody (CAB16109) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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Additional Information
Product Type: |
Antibody |
Reactivity: |
Human |
Host Species: |
Rabbit |
Isotype: |
IgG |
Antibody Type: |
Polyclonal Antibody |
Research Area: |
Cell Biology |
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