Cell Cycle Antibodies 1
Anti-CDK14 Antibody (CAB14986)
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- SKU:
- CAB14986
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-CDK14 Antibody |
| Antibody SKU: | CAB14986 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 312-451 of human CDK14 (NP_036527.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 312-451 of human CDK14 (NP_036527.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AAFP GMKD IQDQ LERI FLVL GTPN EDTW PGVH SLPH FKPE RFTL YSSK NLRQ AWNK LSYV NHAE DLAS KLLQ CSPK NRLS AQAA LSHE YFSD LPPR LWEL TDMS SIFT VPNV RLQP EAGE SMRA FGKN NSYG KSLS NSKH |
| Gene ID: | 5218 |
| Uniprot: | O94921 |
| Cellular Location: | Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein |
| Calculated MW: | 47kDa/50kDa/53kDa |
| Observed MW: | 53kDa |
| Synonyms: | CDK14, PFTAIRE1, PFTK1 |
| Background: |
| UniProt Protein Function: | CDK14: a protein kinase of the CDK family. May play a role in meiosis as well as in neuron differentiation and/or function. Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Two alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.22; Motility/polarity/chemotaxis; Kinase, protein; CMGC group; CDK family; CDK/TAIRE subfamily; TAIRE subfamily Chromosomal Location of Human Ortholog: 7q21-q22 Cellular Component: cytoplasm; plasma membrane; cytosol; nucleus Molecular Function:protein binding; cyclin binding; cyclin-dependent protein kinase activity; ATP binding Biological Process: Wnt receptor signaling pathway; regulation of cell cycle; cell division; G2/M transition of mitotic cell cycle; protein amino acid phosphorylation |
| NCBI Summary: | PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | O94921 |
| NCBI GenInfo Identifier: | 93141297 |
| NCBI Gene ID: | 5218 |
| NCBI Accession: | O94921.3 |
| UniProt Related Accession: | O94921 |
| Molecular Weight: | |
| NCBI Full Name: | Cyclin-dependent kinase 14 |
| NCBI Synonym Full Names: | cyclin dependent kinase 14 |
| NCBI Official Symbol: | CDK14 |
| NCBI Official Synonym Symbols: | PFTK1; PFTAIRE1 |
| NCBI Protein Information: | cyclin-dependent kinase 14 |
| UniProt Protein Name: | Cyclin-dependent kinase 14 |
| UniProt Synonym Protein Names: | Cell division protein kinase 14; Serine/threonine-protein kinase PFTAIRE-1; hPFTAIRE1 |
| UniProt Gene Name: | CDK14 |
| UniProt Entry Name: | CDK14_HUMAN |
 | Western blot analysis of extracts of mouse testis, using CDK14 antibody (CAB14986) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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