Cell Biology Antibodies 5

Anti-CDH9 Antibody (CAB14716)

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SKU:
CAB14716
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CDH9 Antibody
Antibody SKU:CAB14716
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 340-420 of human CDH9 (NP_057363.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:293T, U-87MG, Jurkat, K-562
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 340-420 of human CDH9 (NP_057363.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QMLY TLRV DASN THPD PRFL HLGP FKDT AVVK ISVE DIDE PPVF TKVS YLIE VDED VKEG SIIG QVTA YDPD ARNN LIKY S
Gene ID:1007
Uniprot:Q9ULB4
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:88kDa
Observed MW:120kDa
Synonyms:CDH9
Background:This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
UniProt Protein Function:CDH9: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
UniProt Protein Details:

Protein type:Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 5p14

Cellular Component: plasma membrane

NCBI Summary:This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. [provided by RefSeq, Jul 2008]
UniProt Code:Q9ULB4
NCBI GenInfo Identifier:119370307
NCBI Gene ID:1007
NCBI Accession:Q9ULB4.2
UniProt Secondary Accession:Q9ULB4,Q3B7I5,
UniProt Related Accession:Q9ULB4
Molecular Weight:88,689 Da
NCBI Full Name:Cadherin-9
NCBI Synonym Full Names:cadherin 9
NCBI Official Symbol:CDH9  
NCBI Protein Information:cadherin-9
UniProt Protein Name:Cadherin-9
Protein Family:Cadherin
UniProt Gene Name:CDH9  
UniProt Entry Name:CADH9_HUMAN
Anti-CDH9 Antibody (CAB14716)Western blot analysis of extracts of various cell lines, using CDH9 Rabbit pAb (CAB14716) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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