Cell Biology Antibodies 8
Anti-CDH23 Antibody (CAB2785)
- SKU:
- CAB2785
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CDH23 Antibody |
| Antibody SKU: | CAB2785 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human CDH23 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human CDH23 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 64072 |
| Uniprot: | Q9H251 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 23-27kDa/58kDa/119-133kDa/365- 369kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | CDH23, CDHR23, USH1D |
| Background: | This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. |
| UniProt Code: | Q9H251 |
| NCBI GenInfo Identifier: | 408359994 |
| NCBI Gene ID: | 64072 |
| NCBI Accession: | Q9H251.2 |
| UniProt Secondary Accession: | Q9H251,Q5QGS1, Q5QGS2, Q5QGS5, Q5QGS6, Q5XKN2, Q6UWW1 Q96JL3, Q9H4K9, C4IXS9, F6U049, |
| UniProt Related Accession: | Q9H251 |
| Molecular Weight: | 3354 |
| NCBI Full Name: | Cadherin-23 |
| NCBI Synonym Full Names: | cadherin-related 23 |
| NCBI Official Symbol: | CDH23 |
| NCBI Official Synonym Symbols: | USH1D; CDHR23 |
| NCBI Protein Information: | cadherin-23; otocadherin; cadherin-like 23; cadherin-related family member 23 |
| UniProt Protein Name: | Cadherin-23 |
| UniProt Synonym Protein Names: | Otocadherin |
| Protein Family: | Cadherin |
| UniProt Gene Name: | CDH23 |
| UniProt Entry Name: | CAD23_HUMAN |
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