Cell Biology Antibodies 5
Anti-CDH19 Antibody (CAB14584)
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- SKU:
- CAB14584
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CDH19 Antibody |
| Antibody SKU: | CAB14584 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-440 of human CDH19 (NP_066976.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-440 of human CDH19 (NP_066976.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TSVL IKLS DVND NKPI FKES LYRL TVSE SAPT GTSI GTIM AYDN DIGE NAEM DYSI EEDD SQTF DIIT NHET QEGI VILK KKVD FEHQ NHYG IRAK VKNH HVPE QLMK YHTE ASTT FIKI QVED VDEP PLFL LPYY VFEV FEET PQGS FVGV VSAT DPDN RKSP IRYS ITRS KVFN INDN GTIT TSNS LDRE ISAW YNLS I |
| Gene ID: | 28513 |
| Uniprot: | Q9H159 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 55kDa/87kDa |
| Observed MW: | 87kDa |
| Synonyms: | CDH19, CDH7, CDH7L2 |
| Background: | This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. |
| UniProt Protein Function: | CDH19: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 18q22.1 |
| NCBI Summary: | This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012] |
| UniProt Code: | Q9H159 |
| NCBI GenInfo Identifier: | 17366818 |
| NCBI Gene ID: | 28513 |
| NCBI Accession: | Q9H159.1 |
| UniProt Secondary Accession: | Q9H159,B4E1V5, F5H1K0, |
| UniProt Related Accession: | Q9H159 |
| Molecular Weight: | 55,384 Da |
| NCBI Full Name: | Cadherin-19 |
| NCBI Synonym Full Names: | cadherin 19 |
| NCBI Official Symbol: | CDH19 |
| NCBI Official Synonym Symbols: | CDH7; CDH7L2 |
| NCBI Protein Information: | cadherin-19 |
| UniProt Protein Name: | Cadherin-19 |
| Protein Family: | Cadherin |
| UniProt Gene Name: | CDH19 |
| UniProt Entry Name: | CAD19_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CDH19 antibody (CAB14584) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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