Epigenetics & Nuclear Signaling Antibodies 2

Anti-CDCA7L Antibody (CAB15472)

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SKU:
CAB15472
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-CDCA7L Antibody
Antibody SKU:CAB15472
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDCA7L (NP_061189.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:A-549, Jurkat, Mouse spleen, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDCA7L (NP_061189.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MELA TRYQ IPKE VADI FNAP SDDE EFVG FRDD VPME TLSS EESC DSFD SLES GKQQ DVRF HSKY FTEE LRRI FIED TDSE TEDF AGFT QSDL NGKT NPEV MVVE SDLS DDGK ASLV SEEE EDEE EDKA TPRR SRSR RSSI GLRV AFQF PTKK LANK PDKN SSSE QLFS SARL QNEK KTIL ERKK DCRQ VIQR EDST SESE DDSR DESQ ESSD ALLK RTMN IKEN KAML AQLL AELN SMPD FFPV RTPT SASR KKTV RRAF SEGQ ITRR MNPT RSAR PPEK FALE NFTV SAAK FAEE FYSF
Gene ID:55536
Uniprot:Q96GN5
Cellular Location:Cytoplasm, Nucleus
Calculated MW:46kDa/48kDa/52kDa
Observed MW:52kDa
Synonyms:CDCA7L, JPO2, R1, RAM2
Background:
UniProt Protein Function:Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
UniProt Code:Q96GN5
NCBI GenInfo Identifier:188497635
NCBI Gene ID:55536
NCBI Accession:NP_001120842.1
UniProt Secondary Accession:Q96GN5,Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2 A4D141, A6NF50, B3KTR5, B4DUT3, C9K0Y1,
UniProt Related Accession:Q96GN5
Molecular Weight:49
NCBI Full Name:cell division cycle-associated 7-like protein isoform 2
NCBI Synonym Full Names:cell division cycle associated 7 like
NCBI Official Symbol:CDCA7L  
NCBI Official Synonym Symbols:R1; JPO2; RAM2  
NCBI Protein Information:cell division cycle-associated 7-like protein
UniProt Protein Name:Cell division cycle-associated 7-like protein
UniProt Synonym Protein Names:Protein JPO2; Transcription factor RAM2
UniProt Gene Name:CDCA7L  
Anti-CDCA7L Antibody (CAB15472)Western blot analysis of extracts of various cell lines, using CDCA7L antibody (CAB15472) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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