Cell Biology Antibodies 6
Anti-CD99L2 Antibody (CAB15907)
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- SKU:
- CAB15907
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CD99L2 Antibody |
| Antibody SKU: | CAB15907 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-185 of human CD99L2 (NP_113650.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse brain, Mouse kidney, Mouse liver, Mouse lung, Rat pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-185 of human CD99L2 (NP_113650.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DFDD FNLE DAVK ETSS VKQP WDHT TTTT TNRP GTTR APAK PPGS GLDL ADAL DDQD DGRR KPGI GGRE RWNH VTTT TKRP VTTR APAN TLGN DFDL ADAL DDRN DRDD GRRK PIAG GGGF SDKD LEDI VGGG EYKP DKGK GDGR YGSN DDPG SGMV AEPG |
| Gene ID: | 83692 |
| Uniprot: | Q8TCZ2 |
| Cellular Location: | Cell junction, Cell membrane, Extracellular side, Single-pass type I membrane protein |
| Calculated MW: | 15kDa/20kDa/22kDa/27kDa/28kDa |
| Observed MW: | 28kDa |
| Synonyms: | CD99L2, CD99B, MIC2L1 |
| Background: | This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | CD99L2: Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Homophilic adhesion molecule, but these interactions may not be required for cell aggregation. Belongs to the CD99 family. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: Xq28 Cellular Component: focal adhesion; integral to membrane; plasma membrane Biological Process: cell adhesion |
| NCBI Summary: | This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| UniProt Code: | Q8TCZ2 |
| NCBI GenInfo Identifier: | 296317276 |
| NCBI Gene ID: | 83692 |
| NCBI Accession: | NP_001171737.1 |
| UniProt Related Accession: | Q8TCZ2 |
| Molecular Weight: | 28kDa |
| NCBI Full Name: | CD99 antigen-like protein 2 isoform 4 |
| NCBI Synonym Full Names: | CD99 molecule like 2 |
| NCBI Official Symbol: | CD99L2 |
| NCBI Official Synonym Symbols: | CD99B; MIC2L1 |
| NCBI Protein Information: | CD99 antigen-like protein 2 |
| UniProt Protein Name: | CD99 antigen-like protein 2 |
| UniProt Synonym Protein Names: | MIC2-like protein 1; CD_antigen: CD99 |
| Protein Family: | CD99 antigen-like protein |
| UniProt Gene Name: | CD99L2 |
| UniProt Entry Name: | C99L2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CD99L2 antibody (CAB15907) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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