Cell Biology Antibodies 7

Anti-CD9 Antibody (CAB1703)

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SKU:
CAB1703
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CD9 Antibody
Antibody SKU:CAB1703
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 112-195 of human CD9 (NP_001760.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 112-195 of human CD9 (NP_001760.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SHKD EVIK EVQE FYKD TYNK LKTK DEPQ RETL KAIH YALN CCGL AGGV EQFI SDIC PKKD VLET FTVK SCPD AIKE VFDN KFHI
Gene ID:928
Uniprot:P21926
Cellular Location:Cell membrane, Membrane, Multi-pass membrane protein
Calculated MW:25kDa
Observed MW:23kDa
Synonyms:BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29, CD9
Background:This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.
UniProt Protein Function:CD9: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family.
UniProt Protein Details:

Protein type:Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: extracellular space; focal adhesion; integral to plasma membrane; membrane; plasma membrane; platelet alpha granule membrane

Molecular Function:protein binding

Biological Process: cell adhesion; cell motility; cell surface receptor linked signal transduction; fusion of sperm to egg plasma membrane; paranodal junction assembly; platelet degranulation; receptor internalization

NCBI Summary:This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
UniProt Code:P21926
NCBI GenInfo Identifier:231724
NCBI Gene ID:928
NCBI Accession:P21926.4
UniProt Secondary Accession:P21926,Q5J7W6, Q96ES4, D3DUQ9,
UniProt Related Accession:P21926
Molecular Weight:
NCBI Full Name:CD9 antigen
NCBI Synonym Full Names:CD9 molecule
NCBI Official Symbol:CD9  
NCBI Official Synonym Symbols:MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29  
NCBI Protein Information:CD9 antigen
UniProt Protein Name:CD9 antigen
UniProt Synonym Protein Names:5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD_antigen: CD9
Protein Family:CD9 antigen
UniProt Gene Name:CD9  
Anti-CD9 Antibody (CAB1703)Western blot analysis of extracts of mouse kidney, using CD9 Antibody (CAB1703) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020).
Anti-CD9 Antibody (CAB1703)Immunohistochemistry of paraffin-embedded human smooth muscle using CD9 Rabbit pAb (CAB1703) at dilution of 1:100 (40x lens).
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