Cell Biology Antibodies 17

Anti-CD83 Antibody (CAB4234)

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SKU:
CAB4234
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CD83 Antibody
Antibody SKU:CAB4234
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human CD83
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, Raji, U-937, Mouse liver, Mouse brain, Rat brain
Immunogen:A synthesized peptide derived from human CD83
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9308
Uniprot:Q01151
Cellular Location:
Calculated MW:45kDa
Observed MW:25-80KDa
Synonyms:BL11, HB15
Background:The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Protein Function:CD83: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p23

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Biological Process: negative regulation of interleukin-4 production; positive regulation of interleukin-2 production; defense response; positive regulation of CD4-positive, alpha beta T cell differentiation; signal transduction; response to organic cyclic substance; positive regulation of interleukin-10 production; humoral immune response

NCBI Summary:The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:Q01151
NCBI GenInfo Identifier:232223
NCBI Gene ID:9308
NCBI Accession:Q01151.1
UniProt Secondary Accession:Q01151,Q5THX9,
UniProt Related Accession:Q01151
Molecular Weight:205
NCBI Full Name:CD83 antigen
NCBI Synonym Full Names:CD83 molecule
NCBI Official Symbol:CD83  
NCBI Official Synonym Symbols:BL11; HB15  
NCBI Protein Information:CD83 antigen; hCD83; B-cell activation protein; cell surface protein HB15; cell-surface glycoprotein; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)
UniProt Protein Name:CD83 antigen
UniProt Synonym Protein Names:B-cell activation protein; Cell surface protein HB15; CD_antigen: CD83
Protein Family:CD83 antigen
UniProt Gene Name:CD83  
UniProt Entry Name:CD83_HUMAN
Anti-CD83 Antibody (CAB4234)Western blot - CD83 Rabbit mAb (CAB4234)
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