Cell Biology Antibodies 17
Anti-CD83 Antibody (CAB4234)
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- SKU:
- CAB4234
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CD83 Antibody |
| Antibody SKU: | CAB4234 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CD83 |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Raji, U-937, Mouse liver, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human CD83 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9308 |
| Uniprot: | Q01151 |
| Cellular Location: | |
| Calculated MW: | 45kDa |
| Observed MW: | 25-80KDa |
| Synonyms: | BL11, HB15 |
| Background: | The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Protein Function: | CD83: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 6p23 Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane Biological Process: negative regulation of interleukin-4 production; positive regulation of interleukin-2 production; defense response; positive regulation of CD4-positive, alpha beta T cell differentiation; signal transduction; response to organic cyclic substance; positive regulation of interleukin-10 production; humoral immune response |
| NCBI Summary: | The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q01151 |
| NCBI GenInfo Identifier: | 232223 |
| NCBI Gene ID: | 9308 |
| NCBI Accession: | Q01151.1 |
| UniProt Secondary Accession: | Q01151,Q5THX9, |
| UniProt Related Accession: | Q01151 |
| Molecular Weight: | 205 |
| NCBI Full Name: | CD83 antigen |
| NCBI Synonym Full Names: | CD83 molecule |
| NCBI Official Symbol: | CD83 |
| NCBI Official Synonym Symbols: | BL11; HB15 |
| NCBI Protein Information: | CD83 antigen; hCD83; B-cell activation protein; cell surface protein HB15; cell-surface glycoprotein; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) |
| UniProt Protein Name: | CD83 antigen |
| UniProt Synonym Protein Names: | B-cell activation protein; Cell surface protein HB15; CD_antigen: CD83 |
| Protein Family: | CD83 antigen |
| UniProt Gene Name: | CD83 |
| UniProt Entry Name: | CD83_HUMAN |
 | Western blot - CD83 Rabbit mAb (CAB4234) |
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