Immunology Antibodies 2

Anti-CD80 Antibody (CAB16039)

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SKU:
CAB16039
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-CD80 Antibody
Antibody SKU:CAB16039
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD80 (NP_005182.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Rat lung
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD80 (NP_005182.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGHT RRQG TSPS KCPY LNFF QLLV LAGL SHFC SGVI HVTK EVKE VATL SCGH NVSV EELA QTRI YWQK EKKM VLTM MSGD MNIW PEYK NRTI FDIT NNLS
Gene ID:941
Uniprot:P33681
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:18kDa/29kDa/33kDa
Observed MW:50-75KDa
Synonyms:B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, CD80
Background:The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
UniProt Protein Function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
NCBI Summary:The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
UniProt Code:P33681
NCBI GenInfo Identifier:461606
NCBI Gene ID:941
NCBI Accession:P33681.1
UniProt Secondary Accession:P33681,Q5DTA9, Q5DTB0,
UniProt Related Accession:P33681
Molecular Weight:18,761 Da
NCBI Full Name:T-lymphocyte activation antigen CD80
NCBI Synonym Full Names:CD80 molecule
NCBI Official Symbol:CD80  
NCBI Official Synonym Symbols:B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1  
NCBI Protein Information:T-lymphocyte activation antigen CD80
UniProt Protein Name:T-lymphocyte activation antigen CD80
UniProt Synonym Protein Names:Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80
Protein Family:T-lymphocyte activation antigen
UniProt Gene Name:CD80  
Anti-CD80 Antibody (CAB16039)Western blot analysis of extracts of Rat lung, using CD80 antibody (CAB16039) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 180s.
Anti-CD80 Antibody (CAB16039)Immunohistochemistry of paraffin-embedded human spleen using CD80 Rabbit pAb (CAB16039) at dilution of 1:100 (40x lens).
Anti-CD80 Antibody (CAB16039)Immunofluorescence analysis of Raw264.7 cells using CD80 antibody (CAB16039) at dilution of 1:100. Blue: DAPI for nuclear staining.
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