Immunology Antibodies 3
Anti-CD79a Antibody (CAB19024)
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- SKU:
- CAB19024
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-CD79a Antibody |
| Antibody SKU: | CAB19024 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CD79a |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | Raji |
| Immunogen: | A synthesized peptide derived from human CD79a |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 973 |
| Uniprot: | P11912 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 45-55kDa |
| Observed MW: | 45kDa |
 | Western blot - CD79a Rabbit mAb (CAB19024) |
| Synonyms: | CD79A, IGA, MB-1, CD79a molecule, CD79a |
| Background: | The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Immunoglobulin superfamily Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: B cell receptor complex; cytoplasm; external side of plasma membrane; integral to plasma membrane; lipid raft; multivesicular body; plasma membrane Molecular Function:protein binding Biological Process: B cell activation; B cell differentiation; B cell proliferation; B cell receptor signaling pathway Disease: Agammaglobulinemia 3, Autosomal Recessive |
| NCBI Summary: | The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P11912 |
| NCBI GenInfo Identifier: | 547896 |
| NCBI Gene ID: | 973 |
| NCBI Accession: | P11912.2 |
| UniProt Secondary Accession: | P11912,Q53FB8, A0N775, |
| UniProt Related Accession: | P11912 |
| Molecular Weight: | 20,786 Da |
| NCBI Full Name: | B-cell antigen receptor complex-associated protein alpha chain |
| NCBI Synonym Full Names: | CD79a molecule |
| NCBI Official Symbol: | CD79A |
| NCBI Official Synonym Symbols: | IGA; MB-1 |
| NCBI Protein Information: | B-cell antigen receptor complex-associated protein alpha chain |
| UniProt Protein Name: | B-cell antigen receptor complex-associated protein alpha chain |
| UniProt Synonym Protein Names: | Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen: CD79a |
| Protein Family: | B-cell antigen receptor complex-associated protein |
| UniProt Gene Name: | CD79A |
| UniProt Entry Name: | CD79A_HUMAN |
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