Immunology Antibodies 3

Anti-CD79a Antibody (CAB19024)

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SKU:
CAB19024
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-CD79a Antibody
Antibody SKU:CAB19024
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human CD79a
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human
Positive Samples:Raji
Immunogen:A synthesized peptide derived from human CD79a
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:973
Uniprot:P11912
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:45-55kDa
Observed MW:45kDa
Anti-CD79a Antibody (CAB19024)Western blot - CD79a Rabbit mAb (CAB19024)
Synonyms:CD79A, IGA, MB-1, CD79a molecule, CD79a
Background:The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Protein Function:Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.
UniProt Protein Details:

Protein type:Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: B cell receptor complex; cytoplasm; external side of plasma membrane; integral to plasma membrane; lipid raft; multivesicular body; plasma membrane

Molecular Function:protein binding

Biological Process: B cell activation; B cell differentiation; B cell proliferation; B cell receptor signaling pathway

Disease: Agammaglobulinemia 3, Autosomal Recessive

NCBI Summary:The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Code:P11912
NCBI GenInfo Identifier:547896
NCBI Gene ID:973
NCBI Accession:P11912.2
UniProt Secondary Accession:P11912,Q53FB8, A0N775,
UniProt Related Accession:P11912
Molecular Weight:20,786 Da
NCBI Full Name:B-cell antigen receptor complex-associated protein alpha chain
NCBI Synonym Full Names:CD79a molecule
NCBI Official Symbol:CD79A  
NCBI Official Synonym Symbols:IGA; MB-1  
NCBI Protein Information:B-cell antigen receptor complex-associated protein alpha chain
UniProt Protein Name:B-cell antigen receptor complex-associated protein alpha chain
UniProt Synonym Protein Names:Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen: CD79a
Protein Family:B-cell antigen receptor complex-associated protein
UniProt Gene Name:CD79A  
UniProt Entry Name:CD79A_HUMAN
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