Anti-CD58 Antibody (CAB0806)
- SKU:
- CAB0806
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD58
- Synonyms:
- LFA-3
- Synonyms:
- LFA3
- Synonyms:
- ag3
- Synonyms:
- CD58 molecule
- Research Area:
- Cell Biology
Description
| Product Name: | CD58 Rabbit mAb |
| Product Code: | CAB0806 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CD58, LFA-3, LFA3, ag3, CD58 molecule |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CD58. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | K-562 |
| Immunogen: | A synthesized peptide derived from human CD58. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 965 |
| Uniprot: | P19256 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor, Single-pass type I membrane protein |
| Calculated MW: | 50-75kDa |
| Observed MW: | 55-70KDa |
| UniProt Protein Function: | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
| NCBI Summary: | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
| UniProt Code: | P19256 |
| NCBI GenInfo Identifier: | 126225 |
| NCBI Gene ID: | 965 |
| NCBI Accession: | P19256.1 |
| UniProt Secondary Accession: | P19256,Q5U053, Q6IB65, Q96KI9, A8K7G5, |
| UniProt Related Accession: | P19256 |
| Molecular Weight: | 27,960 Da |
| NCBI Full Name: | Lymphocyte function-associated antigen 3 |
| NCBI Synonym Full Names: | CD58 molecule |
| NCBI Official Symbol: | CD58 |
| NCBI Official Synonym Symbols: | ag3; LFA3; LFA-3 |
| NCBI Protein Information: | lymphocyte function-associated antigen 3 |
| UniProt Protein Name: | Lymphocyte function-associated antigen 3 |
| UniProt Synonym Protein Names: | Surface glycoprotein LFA-3; CD_antigen: CD58 |
| Protein Family: | Lymphocyte function-associated antigen |
| UniProt Gene Name: | CD58 |
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