Description
Product Name: | CD58 Rabbit mAb |
Product Code: | CAB0806 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | CD58, LFA-3, LFA3, ag3, CD58 molecule |
Applications: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human CD58. |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | K-562 |
Immunogen: | A synthesized peptide derived from human CD58. |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 965 |
Uniprot: | P19256 |
Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor, Single-pass type I membrane protein |
Calculated MW: | 50-75kDa |
Observed MW: | 55-70KDa |
UniProt Protein Function: | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
NCBI Summary: | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
UniProt Code: | P19256 |
NCBI GenInfo Identifier: | 126225 |
NCBI Gene ID: | 965 |
NCBI Accession: | P19256.1 |
UniProt Secondary Accession: | P19256,Q5U053, Q6IB65, Q96KI9, A8K7G5, |
UniProt Related Accession: | P19256 |
Molecular Weight: | 27,960 Da |
NCBI Full Name: | Lymphocyte function-associated antigen 3 |
NCBI Synonym Full Names: | CD58 molecule |
NCBI Official Symbol: | CD58 |
NCBI Official Synonym Symbols: | ag3; LFA3; LFA-3 |
NCBI Protein Information: | lymphocyte function-associated antigen 3 |
UniProt Protein Name: | Lymphocyte function-associated antigen 3 |
UniProt Synonym Protein Names: | Surface glycoprotein LFA-3; CD_antigen: CD58 |
Protein Family: | Lymphocyte function-associated antigen |
UniProt Gene Name: | CD58 |