Cell Biology Antibodies 9
Anti-CD48 Antibody (CAB5396)
- SKU:
- CAB5396
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-CD48 Antibody |
Antibody SKU: | CAB5396 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 45-210 of human CD48 (NP_001769.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse pancreas, Mouse spleen, Rat pancreas |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 45-210 of human CD48 (NP_001769.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | ISES LPEN YKQL TWFY TFDQ KIVE WDSR KSKY FESK FKGR VRLD PQSG ALYI SKVQ KEDN STYI MRVL KKTG NEQE WKIK LQVL DPVP KPVI KIEK IEDM DDNC YLKL SCVI PGES VNYT WYGD KRPF PKEL QNSV LETT LMPH NYSR CYTC QVSN SVSS KNGT VC |
Gene ID: | 962 |
Uniprot: | P09326 |
Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
Calculated MW: | 19kDa/27kDa |
Observed MW: | 45kDa |
Synonyms: | CD48, BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48 |
Background: | This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. |
UniProt Code: | P09326 |
NCBI GenInfo Identifier: | |
NCBI Gene ID: | |
NCBI Accession: | P09326.2 |
Molecular Weight: | 28kDa |
NCBI Full Name: | |
UniProt Protein Name: | CD48 antigen |
UniProt Synonym Protein Names: | B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD_antigen: CD48 |
Protein Family: | CD48 antigen |
UniProt Gene Name: | CD48 |
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