Description
system_update_altDatasheet
| SKU: | HDLA002 |
| Size: | 100 µg |
| Clonality: | Monoclonal |
| Clone: | DM28 |
| Synonyms: | T10, cADPr hydrolase 1 |
| Applications: | ELISA, Flow Cyt |
| Recommended Dilution: | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: | Rabbit |
| Isotype: | Rabbit IgG |
| Reactivity: | Human |
| Purification Method: | Purified from cell culture supernatant by affinity chromatography |
| Formulation: | Powder |
| Buffer: | 1XPBS |
| Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Usage: | Research use only |
| Background: | CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia. |
Additional Information
Product Type: |
Rabbit Monoclonal Antibody |
Antibody Type: |
Monoclonal Antibody |
Size: |
100 μg |
Reactivity: |
Human |
Host Species: |
Rabbit |
Antibody Isotype: |
Rabbit Igg |
Clone: |
DM28 |
Synonyms: |
T10, cADPr hydrolase 1 |