Anti-CD38 Antibody (CAB20215)
- SKU:
- CAB20215
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD38
- Synonyms:
- ADPRC 1
- Synonyms:
- ADPRC1
- Research Area:
- Cell Biology
Description
| Product Name: | CD38 Rabbit mAb |
| Product Code: | CAB20215 |
| Size: | 50uL, 100uL |
| Synonyms: | CD38, ADPRC 1, ADPRC1 |
| Applications: | IF, FC, ELISA |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human CD38. |
| Applications: | IF, FC, ELISA |
| Recommended Dilutions: | Elisa 1:500 - 1:2000 FC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human CD38. |
| Purification Method: | Affinity purification |
| Storage: | Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 952 |
| Uniprot: | P28907 |
| Cellular Location: | Membrane, Single-pass type II membrane protein |
| Calculated MW: | 13kDa/34kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | CD38: Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Belongs to the ADP-ribosyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.2.2.6; EC 2.4.99.20; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Hydrolase; Cell surface; Apoptosis; Lyase; Membrane protein, integral; Cell cycle regulation Chromosomal Location of Human Ortholog: 4p15 Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; nucleus Molecular Function:transferase activity; phosphorus-oxygen lyase activity; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity Biological Process: response to drug; response to retinoic acid; metabolic process; positive regulation of transcription, DNA-dependent; positive regulation of insulin secretion; female pregnancy; signal transduction; positive regulation of cell growth; response to estradiol stimulus; B cell receptor signaling pathway; elevation of cytosolic calcium ion concentration; response to hydroperoxide; positive regulation of B cell proliferation; positive regulation of vasoconstriction; response to hypoxia; response to progesterone stimulus; negative regulation of transcription, DNA-dependent; negative regulation of bone resorption; negative regulation of apoptosis |
| NCBI Summary: | CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P28907 |
| NCBI GenInfo Identifier: | 55977782 |
| NCBI Gene ID: | 952 |
| NCBI Accession: | P28907.2 |
| UniProt Secondary Accession: | P28907,O00121, O00122, Q96HY4, |
| UniProt Related Accession: | P28907 |
| Molecular Weight: | 300 |
| NCBI Full Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
| NCBI Synonym Full Names: | CD38 molecule |
| NCBI Official Symbol: | CD38 |
| NCBI Official Synonym Symbols: | T10; ADPRC 1 |
| NCBI Protein Information: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen (p45); NAD(+) nucleosidase; ADP-ribosyl cyclase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase |
| UniProt Protein Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
| UniProt Synonym Protein Names: | 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20); 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD_antigen: CD38 |
| Protein Family: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase |
| UniProt Gene Name: | CD38 |
| UniProt Entry Name: | CD38_HUMAN |
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