Cell Biology Antibodies 2

Anti-CD37 Antibody (CAB10692)

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SKU:
CAB10692
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CD37 Antibody
Antibody SKU:CAB10692
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 112-241 of human CD37 (NP_001765.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 112-241 of human CD37 (NP_001765.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RAQL ERSL RDVV EKTI QKYG TNPE ETAA EESW DYVQ FQLR CCGW HYPQ DWFQ VLIL RGNG SEAH RVPC SCYN LSAT NDST ILDK VILP QLSR LGHL ARSR HSAD ICAV PAES HIYR EGCA QGLQ KWLH NN
Gene ID:951
Uniprot:P11049
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:22kDa/23kDa/31kDa
Observed MW:Refer to figures
Synonyms:CD37, GP52-40, TSPAN26
Background:The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
UniProt Protein Function:CD37: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: immunological synapse; integral to plasma membrane; membrane

Molecular Function:protein binding

Biological Process: cell surface receptor linked signal transduction

NCBI Summary:The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:P11049
NCBI GenInfo Identifier:115983
NCBI Gene ID:951
NCBI Accession:P11049.2
UniProt Secondary Accession:P11049,Q3KPF9, B4DVC1,
UniProt Related Accession:P11049
Molecular Weight:22,563 Da
NCBI Full Name:Leukocyte antigen CD37
NCBI Synonym Full Names:CD37 molecule
NCBI Official Symbol:CD37  
NCBI Official Synonym Symbols:GP52-40; TSPAN26  
NCBI Protein Information:leukocyte antigen CD37
UniProt Protein Name:Leukocyte antigen CD37
UniProt Synonym Protein Names:Tetraspanin-26; Tspan-26; CD_antigen: CD37
Protein Family:Leukocyte antigen
UniProt Gene Name:CD37  
UniProt Entry Name:CD37_HUMAN
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