Anti-CD31/PECAM1 Antibody (CAB20478)
- SKU:
- CAB20478
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD31
- Synonyms:
- Pecam
Description
| Product Name: | CD31/PECAM1 Rabbit pAb |
| Product Code: | CAB20478 |
| Size: | 50uL, 100uL |
| Synonyms: | CD31, Pecam |
| Applications: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of Rat CD31/PECAM1. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse lung, Mouse spleen, Mouse heart, Rat heart |
| Immunogen: | Recombinant protein of Rat CD31/PECAM1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 29583 |
| Uniprot: | Q3SWT0 |
| Calculated MW: | 76kDa |
| Observed MW: | 130KDa |
| UniProt Protein Function: | PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. |
| UniProt Protein Details: | Protein type:Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis Cellular Component: cell surface; external side of plasma membrane; extracellular space; lipid raft; membrane; plasma membrane; ruffle; smooth muscle contractile fiber Molecular Function:protein phosphatase binding Biological Process: angiogenesis; diapedesis; endothelial cell migration; endothelial cell morphogenesis; negative regulation of actin filament polymerization; negative regulation of peptidyl-tyrosine phosphorylation; phagocytosis; positive regulation of cellular extravasation; positive regulation of leukocyte migration; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of cell migration; Rho protein signal transduction; wound healing |
| UniProt Code: | Q3SWT0 |
| NCBI GenInfo Identifier: | 84029389 |
| NCBI Gene ID: | 29583 |
| NCBI Accession: | Q3SWT0.1 |
| UniProt Secondary Accession: | Q3SWT0,P97635, |
| UniProt Related Accession: | Q3SWT0 |
| Molecular Weight: | 76,189 Da |
| NCBI Full Name: | Platelet endothelial cell adhesion molecule |
| NCBI Synonym Full Names: | platelet/endothelial cell adhesion molecule 1 |
| NCBI Official Symbol: | Pecam1 |
| NCBI Official Synonym Symbols: | CD31; Pecam |
| NCBI Protein Information: | platelet endothelial cell adhesion molecule; PECAM-1 |
| UniProt Protein Name: | Platelet endothelial cell adhesion molecule |
| UniProt Synonym Protein Names: | CD_antigen: CD31 |
| UniProt Gene Name: | Pecam1 |
| UniProt Entry Name: | PECA1_RAT |
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