Immunology Antibodies 1

Anti-CD300C Antibody (CAB10420)

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SKU:
CAB10420
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CD300C Antibody
Antibody SKU:CAB10420
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 21-183 of human CD300C (NP_006669.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, Raji, A-549, PC-12, THP-1, Mouse heart, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 21-183 of human CD300C (NP_006669.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GYFP LSHP MTVA GPVG GSLS VQCR YEKE HRTL NKFW CRPP QILR CDKI VETK GSAG KRNG RVSI RDSP ANLS FTVT LENL TEED AGTY WCGV DTPW LRDF HDPI VEVE VSVF PAGT TTAS SPQS SMGT SGPP TKLP VHTW PSVT RKDS PEPS PHPG SLFS NVR
Gene ID:10871
Uniprot:Q08708
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:24kDa
Observed MW:52kDa
Synonyms:CD300C, CLM-6, CMRF-35, CMRF-35A, CMRF35, CMRF35-A1, CMRF35A, CMRF35A1, IGSF16, LIR
Background:
UniProt Protein Function:CD300C: Belongs to the CD300 family
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:transmembrane receptor activity

Biological Process: cellular defense response; immune system process; regulation of immune response; signal transduction

NCBI Summary:The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]
UniProt Code:Q08708
NCBI GenInfo Identifier:1705938
NCBI Gene ID:10871
NCBI Accession:Q08708.1
UniProt Related Accession:Q08708
Molecular Weight:24,830 Da
NCBI Full Name:CMRF35-like molecule 6
NCBI Synonym Full Names:CD300c molecule
NCBI Official Symbol:CD300C  
NCBI Official Synonym Symbols:LIR; CLM-6; CMRF35; IGSF16; CMRF-35; CMRF35A; CMRF-35A; CMRF35A1; CMRF35-A1  
NCBI Protein Information:CMRF35-like molecule 6
UniProt Protein Name:CMRF35-like molecule 6
UniProt Synonym Protein Names:CD300 antigen-like family member C; CMRF35-A1; CMRF-35; Immunoglobulin superfamily member 16; IgSF16; CD_antigen: CD300c
Protein Family:CMRF35-like molecule
UniProt Gene Name:CD300C  
UniProt Entry Name:CLM6_HUMAN
Anti-CD300C Antibody (CAB10420)Western blot analysis of extracts of various cell lines, using CD300C antibody (CAB10420) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
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