Anti-CD239/BCAM Antibody (CAB19724)
- SKU:
- CAB19724
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AU
- Synonyms:
- CD239
- Synonyms:
- LU
- Synonyms:
- MSK19
- Research Area:
- Cell Biology
Description
| Product Name: | CD239/BCAM Rabbit mAb |
| Product Code: | CAB19724 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | AU, CD239, LU, MSK19 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CD239/BCAM |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, Mouse lung, Mouse heart |
| Immunogen: | A synthesized peptide derived from human CD239/BCAM |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4059 |
| Uniprot: | P50895 |
| Calculated MW: | 85kDa |
| Observed MW: | 85KDa |
| UniProt Protein Function: | Laminin alpha-5 receptor. May mediate intracellular signaling. |
| NCBI Summary: | This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
| UniProt Code: | P50895 |
| NCBI GenInfo Identifier: | 92058724 |
| NCBI Gene ID: | 4059 |
| NCBI Accession: | P50895.2 |
| UniProt Secondary Accession: | P50895,Q86VC7, A8MYF9, A9YWT5, A9YWT6, |
| UniProt Related Accession: | P50895 |
| Molecular Weight: | 67,405 Da |
| NCBI Full Name: | Basal cell adhesion molecule |
| NCBI Synonym Full Names: | basal cell adhesion molecule (Lutheran blood group) |
| NCBI Official Symbol: | BCAM |
| NCBI Official Synonym Symbols: | AU; LU; CD239; MSK19 |
| NCBI Protein Information: | basal cell adhesion molecule |
| UniProt Protein Name: | Basal cell adhesion molecule |
| UniProt Synonym Protein Names: | Auberger B antigen; B-CAM cell surface glycoprotein; F8/G253 antigen; Lutheran antigen; Lutheran blood group glycoprotein; CD_antigen: CD239 |
| Protein Family: | Basal cell adhesion molecule |
| UniProt Gene Name: | BCAM |
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