Cell Biology Antibodies 10

Anti-CD200 Antibody (CAB6552)

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SKU:
CAB6552
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CD200 Antibody
Antibody SKU:CAB6552
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human CD200 (NP_005935.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Mouse heart, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human CD200 (NP_005935.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AQVQ VVTQ DERE QLYT PASL KCSL QNAQ EALI VTWQ KKKA VSPE NMVT FSEN HGVV IQPA YKDK INIT QLGL QNST ITFW NITL EDEG CYMC LFNT FGFG KISG TACL TVYV QPIV SLHY KFSE DHLN ITCS ATAR PAPM VFWK VPRS GIEN STVT LSHP NGTT SVTS ILHI KDPK NQVG KEVI CQVL HLGT VTDF KQTV NKGY WFSV PLL
Gene ID:4345
Uniprot:P41217
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:30kDa/31kDa/32kDa
Observed MW:55kDa
Synonyms:CD200, MOX1, MOX2, MRC, OX-2
Background:This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniProt Protein Function:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
NCBI Summary:This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
UniProt Code:P41217
NCBI GenInfo Identifier:311033489
NCBI Gene ID:4345
NCBI Accession:P41217.4
UniProt Secondary Accession:P41217,Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3, B3KQI1, B4DLW9 D3DN65,
UniProt Related Accession:P41217
Molecular Weight:32,975 Da
NCBI Full Name:OX-2 membrane glycoprotein
NCBI Synonym Full Names:CD200 molecule
NCBI Official Symbol:CD200  
NCBI Official Synonym Symbols:MRC; MOX1; MOX2; OX-2  
NCBI Protein Information:OX-2 membrane glycoprotein
UniProt Protein Name:OX-2 membrane glycoprotein
UniProt Synonym Protein Names:CD_antigen: CD200
UniProt Gene Name:CD200  
Anti-CD200 Antibody (CAB6552)Western blot analysis of extracts of various cell lines, using CD200 antibody (CAB6552) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.
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