Cell Biology Antibodies 14
Anti-CD164 Antibody (CAB17030)
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- SKU:
- CAB17030
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CD164 Antibody |
| Antibody SKU: | CAB17030 |
| Antibody Size: | 20uL, 50 uL |
| Application: | IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-162 of human CD164 (NP_006007.2). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-162 of human CD164 (NP_006007.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DKNT TQHP NVTT LAPI SNVT SAPV TSLP LVTT PAPE TCEG RNSC VSCF NVSV VNTT CFWI ECKD ESYC SHNS TVSD CQVG NTTD FCSV STAT PVPT ANST AKPT VQPS PSTT SKTV TTSG TTNN TVTP TSQP VRKS TFD |
| Gene ID: | 8763 |
| Uniprot: | Q04900 |
| Cellular Location: | |
| Calculated MW: | 16kDa/19kDa/20kDa |
| Observed MW: | Refer to figures |
| Synonyms: | CD164, DFNA66, MGC-24, MGC-24v, MUC-24, endolyn |
| Background: | This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. The encoded protein also interacts with the C-X-C chemokine receptor type 4 and may regulate muscle development. Elevated expression of this gene has been observed in human patients with Sezary syndrome, a type of blood cancer, and a mutation in this gene may be associated with impaired hearing. |
| UniProt Protein Function: | Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. |
| NCBI Summary: | This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. The encoded protein also interacts with the C-X-C chemokine receptor type 4 and may regulate muscle development. Elevated expression of this gene has been observed in human patients with Sezary syndrome, a type of blood cancer, and a mutation in this gene may be associated with impaired hearing. [provided by RefSeq, Oct 2016] |
| UniProt Code: | Q04900 |
| NCBI GenInfo Identifier: | 257051036 |
| NCBI Gene ID: | 8763 |
| NCBI Accession: | Q04900.2 |
| UniProt Related Accession: | Q04900 |
| Molecular Weight: | 16kDa; 19kDa; 20kDa |
| NCBI Full Name: | Sialomucin core protein 24 |
| NCBI Synonym Full Names: | CD164 molecule |
| NCBI Official Symbol: | CD164 |
| NCBI Official Synonym Symbols: | DFNA66; MGC-24; MUC-24; MGC-24v; endolyn |
| NCBI Protein Information: | sialomucin core protein 24 |
| UniProt Protein Name: | Sialomucin core protein 24 |
| UniProt Synonym Protein Names: | Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD_antigen: CD164 |
| Protein Family: | CD164 sialomucin-like 2 protein |
| UniProt Gene Name: | CD164 |
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