Name: Anti-CD163L1 Antibody (CAB15578)
Brand: Cell Biology Antibodies 6
SKU: CAB15578
Availability: OutOfStock

Antibody Name:	Anti-CD163L1 Antibody
Antibody SKU:	CAB15578
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human CD163L1 (NP_777601.2).

Application:	WB
Recommended Dilution:	WB 1:200 - 1:2000
Reactivity:	Rat
Positive Samples:	Rat heart, Rat lung

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human CD163L1 (NP_777601.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	DCLH QNDV SVIC SDGA DLEL RLAD GSNN CSGR VEVR IHEQ WWTI CDQN WKNE QALV VCKQ LGCP FSVF GSRR AKPS NEAR DIWI NSIS CTGN ESAL WDCT YDGK AKRT CFRR SDAG VICS DKAD LDLR LVGA HSPC YGRL EVKY QGEW GTVC HDRW STRN AAVV CKQL GCGK PMHV FGMT YFKE ASGP IWLD DVSC IGNE S
Gene ID:	283316
Uniprot:	Q9NR16
Cellular Location:	Cell membrane, Secreted, Single-pass type I membrane protein
Calculated MW:	79kDa/155kDa/159kDa/160kDa
Observed MW:	159kDa

Synonyms:

CD163L1, CD163B, M160, SCARI2, WC1

Background:

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt Protein Function:	CD163L1: a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
UniProt Protein Details:	Protein type:Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13.3 Cellular Component: integral to membrane; extracellular region; plasma membrane Molecular Function:scavenger receptor activity Biological Process: receptor-mediated endocytosis
NCBI Summary:	This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
UniProt Code:	Q9NR16
NCBI GenInfo Identifier:	50659091
NCBI Gene ID:	283316
NCBI Accession:	NP_777601.2
UniProt Secondary Accession:	Q9NR16,Q2M3B7, Q6UWC2, B4E0G7, C9JHR7, E7EVK4,
UniProt Related Accession:	Q9NR16
Molecular Weight:	159,239 Da
NCBI Full Name:	scavenger receptor cysteine-rich type 1 protein M160 isoform 2
NCBI Synonym Full Names:	CD163 molecule-like 1
NCBI Official Symbol:	CD163L1
NCBI Official Synonym Symbols:	M160; CD163B
NCBI Protein Information:	scavenger receptor cysteine-rich type 1 protein M160; CD163 antigen B; CD163 antigen-like 1
UniProt Protein Name:	Scavenger receptor cysteine-rich type 1 protein M160
UniProt Synonym Protein Names:	CD163 antigen-like 1; CD_antigen: CD163b
Protein Family:	Scavenger receptor cysteine-rich type 1 protein
UniProt Gene Name:	CD163L1
UniProt Entry Name:	C163B_HUMAN

Western blot analysis of extracts of various cell lines, using CD163L1 Rabbit pAb (CAB15578) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.

Antibodies

Anti-CD163L1 Antibody (CAB15579)

CD163L1 Antibody (PACO02092)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)