Cell Biology Antibodies 8

Anti-CCT6A Antibody (CAB3589)

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SKU:
CAB3589
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CCT6A Antibody
Antibody SKU:CAB3589
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-250 of human CCT6A (NP_001753.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:BT-474, U-251MG, HeLa, SKOV3, Mouse kidney, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-250 of human CCT6A (NP_001753.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VATA QDDI TGDG TTSN VLII GELL KQAD LYIS EGLH PRII TEGF EAAK EKAL QFLE EVKV SREM DRET LIDV ARTS LRTK VHAE LADV LTEA VVDS ILAI KKQD EPID LFMI EIME MKHK SETD TSLI RGLV LDHG ARHP DMKK RVED AYIL TCNV SLEY EKTE VNSG FFY
Gene ID:908
Uniprot:P40227
Cellular Location:Cytoplasm
Calculated MW:53kDa/58kDa
Observed MW:58kDa
Synonyms:CCT6A, CCT-zeta, CCT-zeta-1, CCT6, Cctz, HTR3, MoDP-2, TCP-1-zeta, TCP20, TCPZ, TTCP20
Background:The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located.
UniProt Protein Function:Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
NCBI Summary:The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010]
UniProt Code:P40227
NCBI GenInfo Identifier:58331171
NCBI Gene ID:908
NCBI Accession:NP_001009186.1
UniProt Secondary Accession:P40227,Q3KP28, Q75LP4, Q96S46, A6NCD2,
UniProt Related Accession:P40227
Molecular Weight:53,289 Da
NCBI Full Name:T-complex protein 1 subunit zeta isoform b
NCBI Synonym Full Names:chaperonin containing TCP1 subunit 6A
NCBI Official Symbol:CCT6A  
NCBI Official Synonym Symbols:CCT6; Cctz; HTR3; TCPZ; TCP20; MoDP-2; TTCP20; CCT-zeta; CCT-zeta-1; TCP-1-zeta  
NCBI Protein Information:T-complex protein 1 subunit zeta
UniProt Protein Name:T-complex protein 1 subunit zeta
UniProt Synonym Protein Names:Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20
Protein Family:T-complex protein
UniProt Gene Name:CCT6A  
Anti-CCT6A Antibody (CAB3589)Western blot analysis of extracts of various cell lines, using CCT6A antibody (CAB3589) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-CCT6A Antibody (CAB3589)Immunohistochemistry of paraffin-embedded human stomach using CCT6A antibody (CAB3589) at dilution of 1:100 (40x lens).
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