Description
| Antibody Name: | Anti-CCR9 Antibody |
| Antibody SKU: | CAB17087 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human CCR9. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide of human CCR9. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10803 |
| Uniprot: | P51686 |
| Cellular Location: | |
| Calculated MW: | 40kDa/42kDa |
| Observed MW: | Refer to figures |
| Synonyms: | CCR9, CC-CKR-9, CDw199, GPR-9-6, GPR28 |
| Background: | The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | CCR9: Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: cell surface; integral to plasma membrane; plasma membrane Molecular Function:C-C chemokine receptor activity; chemokine receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cellular defense response; immune response; chemotaxis |
| NCBI Summary: | The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| UniProt Code: | P51686 |
| NCBI GenInfo Identifier: | 114152781 |
| NCBI Gene ID: | 10803 |
| NCBI Accession: | P51686.2 |
| UniProt Secondary Accession: | P51686,Q9WUT7, |
| UniProt Related Accession: | P51686 |
| Molecular Weight: | 40,713 Da |
| NCBI Full Name: | C-C chemokine receptor type 9 |
| NCBI Synonym Full Names: | chemokine (C-C motif) receptor 9 |
| NCBI Official Symbol: | CCR9 |
| NCBI Official Synonym Symbols: | GPR28; CDw199; GPR-9-6; CC-CKR-9 |
| NCBI Protein Information: | C-C chemokine receptor type 9; G protein-coupled receptor 28 |
| UniProt Protein Name: | C-C chemokine receptor type 9 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 28; GPR-9-6; CD_antigen: CDw199 |
| Protein Family: | C-C chemokine receptor |
| UniProt Gene Name: | CCR9 |
| UniProt Entry Name: | CCR9_HUMAN |
Additional Information
Product Type: |
Antibody |
Reactivity: |
Human |
Reactivity: |
Rat |
Host Species: |
Rabbit |
Isotype: |
IgG |
Antibody Type: |
Polyclonal Antibody |
Research Area: |
Immunology |
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