Cell Biology Antibodies 14
Anti-CCNT2 Antibody (CAB16802)
- SKU:
- CAB16802
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-CCNT2 Antibody |
Antibody SKU: | CAB16802 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human CCNT2 (NP_001232.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human CCNT2 (NP_001232.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | RLKK IRNW RANQ AARK PKVD GQVS ETPL LGSS LVQN SILV DSVT GVPT NPSF QKPS TSAF PAPV PLNS GNIS VQDS HTSD NLSM LATG MPST SYGL SSHQ EWPQ HQDS ARTE QLYS QKQE TSLS GSQY NINF QQGP SISL HSGL HHRP DKIS DHSS VKQE YTHK AGSS KHHG PIST TPGI IPQK MSLD KYRE KRKL ETLD LDVR DHYI AAQV EQQH KQGQ SQAA SSSS VTSP IKMK IPIA NTEK YMAD KKEK SGSL KLRI PIPP TDKS ASKE ELKM KIKV SSSE RHSS SDEG SGKS KHSS P |
Gene ID: | 905 |
Uniprot: | O60583 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | Refer to figures |
Synonyms: | CCNT2, CYCT2, cyclin-T2 |
Background: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants. |
NCBI Summary: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] |
UniProt Code: | O60583 |
NCBI GenInfo Identifier: | 89130720 |
NCBI Gene ID: | 905 |
NCBI Accession: | AAI14367.1 |
UniProt Related Accession: | O60583 |
Molecular Weight: | 81kDa |
NCBI Full Name: | Cyclin T2 |
NCBI Synonym Full Names: | cyclin T2 |
NCBI Official Symbol: | CCNT2 |
NCBI Official Synonym Symbols: | CYCT2 |
NCBI Protein Information: | cyclin-T2 |
UniProt Protein Name: | Cyclin-T2 |
Protein Family: | Cyclin |
UniProt Gene Name: | CCNT2 |
UniProt Entry Name: | CCNT2_HUMAN |