| UniProt Protein Function: | CCNO: This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 term is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes.[provided by RefSeq, Nov 2010] Protein type: EC 3.2.2.-; Hydrolase; Cell cycle regulation; DNA repair, damage Chromosomal Location of Human Ortholog: 5q11.2 Cellular Component: cytoplasm; nucleoplasm Molecular Function: uracil DNA N-glycosylase activity Biological Process: base-excision repair; cell cycle; cell division; cilium biogenesis Disease: Ciliary Dyskinesia, Primary, 29 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the cyclin protein family, and the encoded protein is involved in regulation of the cell cycle. Disruption of this gene is associated with primary ciliary dyskinesia-19. Alternative splicing results in multiple transcript variants. This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 symbol is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes. [provided by RefSeq, Jul 2014] |
| UniProt Code: | P22674 |
| NCBI GenInfo Identifier: | 118572733 |
| NCBI Gene ID: | 10309 |
| NCBI Accession: | P22674.2 |
| UniProt Secondary Accession: | P22674,Q0P6J2, Q9H6B0, Q9UMD5, A8K1W5 |
| UniProt Related Accession: | P22674 |
| Molecular Weight: | 14,297 Da |
| NCBI Full Name: | Cyclin-O |
| NCBI Synonym Full Names: | cyclin O |
| NCBI Official Symbol: | CCNO |
| NCBI Official Synonym Symbols: | CCNU; UDG2; CILD29 |
| NCBI Protein Information: | cyclin-O |
| UniProt Protein Name: | Cyclin-O |
| UniProt Synonym Protein Names: | |
| Protein Family: | Cyclin |
| UniProt Gene Name: | CCNO |
| UniProt Entry Name: | CCNO_HUMAN |
