Cell Biology Antibodies 8
Anti-CCL17 Antibody (CAB2854)
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- SKU:
- CAB2854
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-CCL17 Antibody (CAB2854) |
| Antibody SKU: | CAB2854 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting, Immunohistochemistry |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-94 of human CCL17 (NP_002978.1). |
| Application: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Raji, THP-1, Mouse testis, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-94 of human CCL17 (NP_002978.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ARGT NVGR ECCL EYFK GAIP LRKL KTWY QTSE DCSR DAIV FVTV QGRA ICSD PNNK RVKN AVKY LQSL ERS |
| Cellular Location: | Secreted |
| Calculated MW: | 10kDa |
| Observed MW: | 11KDa |
| Synonyms: | CCL17, A-152E5.3, ABCD-2, SCYA17, TARC |
| Background: | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. |
 | Western blot analysis of extracts of various cell lines, using CCL17 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s. |
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