Anti-CCDC98 Antibody (CAB9421)
- SKU:
- CAB9421
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-CCDC98 Antibody (CAB9421) |
| Antibody SKU: | CAB9421 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting, Immunoprecipitation |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CCDC98. |
| Application: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:500 - 1:2000 IP 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | 293T, MCF7, SKOV3 |
| Immunogen: | A synthesized peptide derived from human CCDC98. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Cellular Location: | Nucleus |
| Calculated MW: | 50kDa |
| Observed MW: | 50KDa |
| Synonyms: | FAM175A, ABRA1, CCDC98, BRCA1-A complex subunit Abraxas |
| Background: | This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. |
 | Immunoprecipitation analysis of 300ug extracts of MCF7 cells using 3ug CCDC98 antibody . Western blot was performed from the immunoprecipitate using CCDC98 antibody at a dilition of 1:500. |
 | Western blot analysis of extracts of various cell lines, using at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s. |
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