Metabolism Antibodies 2
Anti-CBR4 Antibody (CAB5069)
- SKU:
- CAB5069
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CBR4
- Synonyms:
- SDR45C1
- Research Area:
- Metabolism
Description
| Product Name: | CBR4 Rabbit pAb |
| Product Code: | CAB5069 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CBR4, SDR45C1 |
| Applications: | WB, IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human CBR4 (NP_116172.2). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:200 - 1:2000 IHC 1:20 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | Jurkat, MCF7, 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human CBR4 (NP_116172.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDKV CAVF GGSR GIGR AVAQ LMAR KGYR LAVI ARNL EGAK AAAG DLGG DHLA FSCD VAKE HDVQ NTFE ELEK HLGR VNFL VNAA GINR DGLL VRTK TEDM VSQL HTNL LGSM LTCK AAMR TMIQ QQGG SIVN VGSI VGLK GNSG QSVY SASK GGLV GFSR ALAK EVAR KKIR VNVV APGF VHTD MTKD LKEE HLKK NIPL GRFG ETIE VAHA VVFL LESP YITG HVLV VDGG LQLI L |
| Gene ID: | 84869 |
| Uniprot: | Q8N4T8 |
| Cellular Location: | Mitochondrion matrix |
| Calculated MW: | 18kDa/25kDa |
| Observed MW: | 25kDa |
| UniProt Protein Function: | CBR4: The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.-.-.-; Oxidoreductase; Mitochondrial; EC 1.1.1.- Chromosomal Location of Human Ortholog: 4q32.3 Cellular Component: mitochondrial matrix Molecular Function:protein binding; NAD(P)H dehydrogenase (quinone) activity; NADPH dehydrogenase (quinone) activity; quinone binding Biological Process: fatty acid biosynthetic process; protein homotetramerization |
| UniProt Code: | Q8N4T8 |
| NCBI GenInfo Identifier: | 269849708 |
| NCBI Gene ID: | 84869 |
| NCBI Accession: | Q8N4T8.3 |
| UniProt Secondary Accession: | Q8N4T8,Q8WTW8, Q96K93, |
| UniProt Related Accession: | Q8N4T8 |
| Molecular Weight: | 237 |
| NCBI Full Name: | Carbonyl reductase family member 4 |
| NCBI Synonym Full Names: | carbonyl reductase 4 |
| NCBI Official Symbol: | CBR4 |
| NCBI Official Synonym Symbols: | SDR45C1 |
| NCBI Protein Information: | carbonyl reductase family member 4; carbonic reductase 4; quinone reductase CBR4; 3-oxoacyl-[acyl-carrier-protein] reductase; short chain dehydrogenase/reductase family 45C, member 1 |
| UniProt Protein Name: | Carbonyl reductase family member 4 |
| UniProt Synonym Protein Names: | 3-oxoacyl-[acyl-carrier-protein] reductase (EC:1.1.1.-); Quinone reductase CBR4 |
| Protein Family: | Carbonyl reductase family |
| UniProt Gene Name: | CBR4 |
| UniProt Entry Name: | CBR4_HUMAN |
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