Cell Death Antibodies 1

Anti-CARD6 Antibody (CAB13806)

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SKU:
CAB13806
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death

Description

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Antibody Name:Anti-CARD6 Antibody
Antibody SKU:CAB13806
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CARD6 (NP_115976.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HT-29, MCF7, 293T, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CARD6 (NP_115976.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MATE STPS EIIE RERK KLLE ILQH DPDS ILDT LTSR RLIS EEEY ETLE NVTD LLKK SRKL LILV QKKG EATC QHFL KCLF STFP QSAA ICGL RHEV LKHE NTVP PQSM GASS NSED AFSP GIKQ PEAP EITV FFSE KEHL DLET SEFF RDKK TSYR ETAL SARK NEKE YDTP EVTL SYSV EKVG CEVP ATIT YIKD GQRY
Gene ID:84674
Uniprot:Q9BX69
Cellular Location:
Calculated MW:116kDa
Observed MW:116kDa
Synonyms:CARD6, CINCIN1
Background:This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
UniProt Protein Function:CARD6: May be involved in apoptosis.
UniProt Protein Details:

Protein type:Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5p13.1

NCBI Summary:This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BX69
NCBI GenInfo Identifier:209572595
NCBI Gene ID:84674
NCBI Accession:Q9BX69.2
UniProt Secondary Accession:Q9BX69,Q52LR2,
UniProt Related Accession:Q9BX69
Molecular Weight:116,468 Da
NCBI Full Name:Caspase recruitment domain-containing protein 6
NCBI Synonym Full Names:caspase recruitment domain family member 6
NCBI Official Symbol:CARD6  
NCBI Official Synonym Symbols:CINCIN1  
NCBI Protein Information:caspase recruitment domain-containing protein 6
UniProt Protein Name:Caspase recruitment domain-containing protein 6
Protein Family:Caspase recruitment domain-containing protein
UniProt Gene Name:CARD6  
Anti-CARD6 Antibody (CAB13806)Western blot analysis of extracts of various cell lines, using CARD6 antibody (CAB13806) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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