Cell Biology Antibodies 12
Anti-Carboxypeptidase Q Antibody (CAB8478)
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- SKU:
- CAB8478
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Carboxypeptidase Q Antibody |
| Antibody SKU: | CAB8478 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human CPQ (NP_057218.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human CPQ (NP_057218.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GKAI CKNG ISKR TFEE IKEE IASC GDVA KAII NLAV YGKA QNRS YERL ALLV DTVG PRLS GSKN LEKA IQIM YQNL QQDG LEKV HLEP VRIP HWER GEES AVML EPRI HKIA ILGL GSSI GTPP EGIT AEVL VVTS FDEL QRRA SEAR GKIV VYNQ PYIN YSRT VQYR TQGA VEAA KVGA L |
| Gene ID: | 10404 |
| Uniprot: | Q9Y646 |
| Cellular Location: | Endoplasmic reticulum, Golgi apparatus, Lysosome, Secreted |
| Calculated MW: | 51kDa |
| Observed MW: | 60kDa |
| Synonyms: | CPQ, LDP, PGCP |
| Background: | This gene encodes a metallopeptidase that belongs to the peptidase M28 family. The encoded protein may catalyze the cleavage of dipeptides with unsubstituted terminals into amino acids. |
| UniProt Protein Function: | PGCP: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes more efficiently the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in thyroxin hormone liberation from its TG/thyroglobulin precursor. Belongs to the peptidase M28 family. |
| UniProt Protein Details: | Protein type:EC 3.4.17.-; Protease; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 8q22.1 Cellular Component: cytoplasm; endoplasmic reticulum; extracellular space; Golgi apparatus; lysosome Molecular Function:protein homodimerization activity Biological Process: peptide catabolic process; proteolysis; thyroid hormone generation; tissue regeneration |
| NCBI Summary: | This gene encodes a metallopeptidase that belongs to the peptidase M28 family. The encoded protein may catalyze the cleavage of dipeptides with unsubstituted terminals into amino acids. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9Y646 |
| NCBI GenInfo Identifier: | 74735298 |
| NCBI Gene ID: | 10404 |
| NCBI Accession: | Q9Y646.1 |
| UniProt Secondary Accession: | Q9Y646,Q8NBZ1, Q9UNM8, Q9Y5X6, B2RD88, |
| UniProt Related Accession: | Q9Y646 |
| Molecular Weight: | 52kDa |
| NCBI Full Name: | Carboxypeptidase Q |
| NCBI Synonym Full Names: | carboxypeptidase Q |
| NCBI Official Symbol: | CPQ |
| NCBI Official Synonym Symbols: | LDP; PGCP |
| NCBI Protein Information: | carboxypeptidase Q |
| UniProt Protein Name: | Carboxypeptidase Q |
| UniProt Synonym Protein Names: | Lysosomal dipeptidase; Plasma glutamate carboxypeptidase |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPQ |
 | Western blot analysis of extracts of mouse liver, using CPQ antibody (CAB8478) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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