Cell Biology Antibodies 17

Anti-Carbonic Anhydrase 1 Antibody (CAB4406)

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SKU:
CAB4406
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-Carbonic Anhydrase 1 Antibody
Antibody SKU:CAB4406
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Carbonic Anhydrase 1
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Mouse spleen, Rat liver, Rat kidney
Immunogen:A synthesized peptide derived from human Carbonic Anhydrase 1
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:759
Uniprot:P00915
Cellular Location:
Calculated MW:29kDa
Observed MW:29KDa
Synonyms:CA-I, CAB, Car1, HEL-S-11
Background:Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]
UniProt Protein Function:CA1: Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. Belongs to the alpha-carbonic anhydrase family.
UniProt Protein Details:

Protein type:EC 4.2.1.1; Energy Metabolism - nitrogen; Lyase

Chromosomal Location of Human Ortholog: 8q21.2

Cellular Component: cytosol

Molecular Function:carbonate dehydratase activity; zinc ion binding

Biological Process: bicarbonate transport; one-carbon compound metabolic process

NCBI Summary:Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
UniProt Code:P00915
NCBI GenInfo Identifier:115449
NCBI Gene ID:759
NCBI Accession:P00915.2
UniProt Related Accession:P00915
Molecular Weight:261
NCBI Full Name:Carbonic anhydrase 1
NCBI Synonym Full Names:carbonic anhydrase I
NCBI Official Symbol:CA1  
NCBI Official Synonym Symbols:CAB; CA-I; Car1; HEL-S-11  
NCBI Protein Information:carbonic anhydrase 1; carbonic anhydrase B; carbonate dehydratase I; epididymis secretory protein Li 11
UniProt Protein Name:Carbonic anhydrase 1
UniProt Synonym Protein Names:Carbonate dehydratase I; Carbonic anhydrase B; CAB; Carbonic anhydrase I; CA-I
Protein Family:Cation-transporting ATPase
UniProt Gene Name:CA1  
UniProt Entry Name:CAH1_HUMAN
Anti-Carbonic Anhydrase 1 Antibody (CAB4406)Western blot - Carbonic Anhydrase 1 Rabbit mAb (CAB4406)
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