Cell Biology Antibodies 13
Anti-CAPN13 Antibody (CAB17244)
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- SKU:
- CAB17244
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CAPN13 Antibody |
| Antibody SKU: | CAB17244 |
| Antibody Size: | 20uL, 50 uL |
| Application: | IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CAPN13 (NP_653176.2). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CAPN13 (NP_653176.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAYY QEPS VETS IIKF KDQD FTTL RDHC LSMG RTFK DETF PAAD SSIG QKLL QEKR LSNV IWKR PQDL PGGP PHFI LDDI SRFD IQQG GAAD CWFL AALG SLTQ NPQY RQKI LMVQ SFSH QYAG IFRF RFWQ CGQW VEVV IDDR LPVQ GDKC LFVR PRHQ NQEF WPCL LEKA YAKL LGSY SDLH YGFL EDAL VDLT GGVI |
| Gene ID: | 92291 |
| Uniprot: | Q6MZZ7 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | CAPN13 |
| Background: | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. |
| UniProt Protein Function: | CAPN13: Probable non-lysosomal thiol-protease. Belongs to the peptidase C2 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.22.-; Protease Chromosomal Location of Human Ortholog: 2p22-p21 Cellular Component: cytoplasm Molecular Function:calcium-dependent cysteine-type endopeptidase activity Biological Process: proteolysis |
| NCBI Summary: | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012] |
| UniProt Code: | Q6MZZ7 |
| NCBI GenInfo Identifier: | 117949375 |
| NCBI Gene ID: | 92291 |
| NCBI Accession: | Q6MZZ7.2 |
| UniProt Secondary Accession: | Q6MZZ7,Q17RF0, Q580X1, Q8TE80, |
| UniProt Related Accession: | Q6MZZ7 |
| Molecular Weight: | 48,002 Da |
| NCBI Full Name: | Calpain-13 |
| NCBI Synonym Full Names: | calpain 13 |
| NCBI Official Symbol: | CAPN13 |
| NCBI Protein Information: | calpain-13 |
| UniProt Protein Name: | Calpain-13 |
| UniProt Synonym Protein Names: | Calcium-activated neutral proteinase 13; CANP 13 |
| Protein Family: | Calpain |
| UniProt Gene Name: | CAPN13 |
| UniProt Entry Name: | CAN13_HUMAN |
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