Cell Biology Antibodies 2

Anti-CALY Antibody (CAB10499)

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SKU:
CAB10499
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CALY Antibody
Antibody SKU:CAB10499
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human CALY (NP_056537.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human CALY (NP_056537.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MVKL GCSF SGKP GKDP GDQD GAAM DSVP LISP LDIS QLQP PLPD QVVI KTQT EYQL SSPD QQNF PDLE GQRL NCSH PEEG RRLP TAR
Gene ID:50632
Uniprot:Q9NYX4
Cellular Location:Cell membrane, Cytoplasmic vesicle membrane, Single-pass membrane protein
Calculated MW:13kDa/17kDa/23kDa
Observed MW:24kDa
Synonyms:CALY, DRD1IP, NSG3
Background:The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs.
UniProt Protein Function:calcyon: Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. Belongs to the NSG family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q26.3

Cellular Component: cytoplasmic vesicle; integral to plasma membrane

Molecular Function:clathrin light chain binding; protein binding

Biological Process: clathrin cage assembly; positive regulation of endocytosis

NCBI Summary:The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NYX4
NCBI GenInfo Identifier:17374622
NCBI Gene ID:50632
NCBI Accession:Q9NYX4.1
UniProt Secondary Accession:Q9NYX4,Q5VWX3, Q5VWY5, Q5VWY6,
UniProt Related Accession:Q9NYX4
Molecular Weight:17,547 Da
NCBI Full Name:Neuron-specific vesicular protein calcyon
NCBI Synonym Full Names:calcyon neuron specific vesicular protein
NCBI Official Symbol:CALY  
NCBI Official Synonym Symbols:NSG3; DRD1IP  
NCBI Protein Information:neuron-specific vesicular protein calcyon
UniProt Protein Name:Neuron-specific vesicular protein calcyon
Protein Family:Neuron-specific vesicular protein calcyon
UniProt Gene Name:CALY  
UniProt Entry Name:CALY_HUMAN
Anti-CALY Antibody (CAB10499)Western blot analysis of extracts of mouse testis, using CALY antibody (CAB10499) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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