Cell Biology Antibodies 11

Anti-CALML5 Antibody (CAB7808)

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SKU:
CAB7808
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CALML5 Antibody
Antibody SKU:CAB7808
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human CALML5 (NP_059118.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse eye, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human CALML5 (NP_059118.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAGE LTPE EEAQ YKKA FSAV DTDG NGTI NAQE LGAA LKAT GKNL SEAQ LRKL ISEV DSDG DGEI SFQE FLTA AKKA RAGL EDLQ VAFR AFDQ DGDG HITV DELR RAMA GLGQ PLPQ EELD AMIR EADV DQDG RVNY EEFA RMLA QE
Gene ID:51806
Uniprot:Q9NZT1
Cellular Location:
Calculated MW:15kDa
Observed MW:16kDa
Synonyms:CALML5, CLSP
Background:This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
UniProt Protein Function:Binds calcium. May be involved in terminal differentiation of keratinocytes.
NCBI Summary:This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NZT1
NCBI GenInfo Identifier:215273944
NCBI Gene ID:51806
NCBI Accession:Q9NZT1.2
UniProt Secondary Accession:Q9NZT1,Q5SQI3, Q8IXU8,
UniProt Related Accession:Q9NZT1
Molecular Weight:15,893 Da
NCBI Full Name:Calmodulin-like protein 5
NCBI Synonym Full Names:calmodulin like 5
NCBI Official Symbol:CALML5  
NCBI Official Synonym Symbols:CLSP  
NCBI Protein Information:calmodulin-like protein 5
UniProt Protein Name:Calmodulin-like protein 5
UniProt Synonym Protein Names:Calmodulin-like skin protein
UniProt Gene Name:CALML5  
Anti-CALML5 Antibody (CAB7808)Western blot analysis of extracts of various cell lines, using CALML5 antibody (CAB7808) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-CALML5 Antibody (CAB7808)Immunohistochemistry of paraffin-embedded mouse brain using CALML5 antibody (CAB7808) at dilution of 1:100 (40x lens).
Anti-CALML5 Antibody (CAB7808)Immunohistochemistry of paraffin-embedded mouse stomach using CALML5 antibody (CAB7808) at dilution of 1:100 (40x lens).
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