Cell Biology Antibodies 11
Anti-CALCB Antibody (CAB8105)
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- SKU:
- CAB8105
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | CALCB Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8105 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human CALCB (NP_000719.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human CALCB (NP_000719.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGFR KFSP FLAL SILV LYQA GSLQ AAPF RSAL ESSP DPAT LSKE DARL LLAA LVQD YVQM KASE LKQE QETQ GSSS AAQK RACN TATC VTHR LAGL LSRS GGMV KSNF VPTN VGSK AFGR RRRD LQA |
| Gene ID: | 797 |
| Uniprot: | P10092 |
| Cellular Location: | Secreted |
| Calculated MW: | 13kDa |
| Observed MW: | 14kDa |
| Synonyms: | CALCB, CALC2, CGRP-II, CGRP2 |
| Background: |
| UniProt Protein Function: | CALCB: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. Belongs to the calcitonin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 11p15.2-p15.1 Cellular Component: extracellular region Molecular Function:neuropeptide hormone activity Biological Process: cellular calcium ion homeostasis; signal transduction |
| UniProt Code: | P10092 |
| NCBI GenInfo Identifier: | 9945304 |
| NCBI Gene ID: | 797 |
| NCBI Accession: | NP_000719.1 |
| UniProt Secondary Accession: | P10092,Q569I0, Q9UCN9, A8K573, D3DQX4, |
| UniProt Related Accession: | P10092 |
| Molecular Weight: | Predicted Molecular Mass: 15.0kDaAccurate Molecular Mass: 19kDa as determined by SDS-PAGE reducing conditions. |
| NCBI Full Name: | calcitonin gene-related peptide 2 |
| NCBI Synonym Full Names: | calcitonin-related polypeptide beta |
| NCBI Official Symbol: | CALCB |
| NCBI Official Synonym Symbols: | CALC2; CGRP2; CGRP-II |
| NCBI Protein Information: | calcitonin gene-related peptide 2; beta-CGRP; calcitonin 2; beta-type CGRP; calcitonin gene-related peptide II |
| UniProt Protein Name: | Calcitonin gene-related peptide 2 |
| UniProt Synonym Protein Names: | Beta-type CGRP; Beta-CGRP; Calcitonin gene-related peptide II |
| UniProt Gene Name: | CALCB |
| UniProt Entry Name: | CALCB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CALCB antibody (CAB8105) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunohistochemistry of paraffin-embedded rat heart using CALCB antibody (CAB8105) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human prostate using CALCB antibody (CAB8105) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse lung using CALCB antibody (CAB8105) at dilution of 1:100 (40x lens). |
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