Cell Biology Antibodies 9
Anti-CADM3 Antibody (CAB4902)
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- SKU:
- CAB4902
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CADM3
- Synonyms:
- BIgR
- Synonyms:
- IGSF4B
- Synonyms:
- NECL1
- Synonyms:
- Necl-1
- Synonyms:
- TSLL1
- Synonyms:
- synCAM3
- Research Area:
- Cell Biology
Description
| Product Name: | CADM3 Rabbit pAb |
| Product Code: | CAB4902 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CADM3, BIgR, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, MCF7, HL-60, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NLSQ DDSQ PWTS DETV VAGG TVVL KCQV KDHE DSSL QWSN PAQQ TLYF GEKR ALRD NRIQ LVTS TPHE LSIS ISNV ALAD EGEY TCSI FTMP VRTA KSLV TVLG IPQK PIIT GYKS SLRE KDTA TLNC QSSG SKPA ARLT WRKG DQEL HGEP TRIQ EDPN GKTF TVSS SVTF QVTR EDDG ASIV CSVN HESL KGAD RSTS QRIE VLYT PTAM IRPD PPHP REGQ KLLL HCEG RGNP VPQQ YLWE KEGS VPPL KMTQ ESAL IFPF LNKS DSGT YGCT ATSN MGSY KAYY TLNV NDPS PVPS SSST YH |
| Gene ID: | 57863 |
| Uniprot: | Q8N126 |
| Cellular Location: | Cell junction, Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 38kDa/43kDa/47kDa |
| Observed MW: | 43kDa |
| UniProt Protein Function: | CADM3: Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. Belongs to the nectin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q21.2-q22 Cellular Component: cell-cell adherens junction; integral to plasma membrane; intercellular junction; plasma membrane Molecular Function:cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion; intercellular junction assembly and maintenance; protein localization |
| NCBI Summary: | IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005 [PubMed 15741237]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8N126 |
| NCBI GenInfo Identifier: | 74759761 |
| NCBI Gene ID: | 57863 |
| NCBI Accession: | Q8N126.1 |
| UniProt Secondary Accession: | Q8N126,Q8IZQ9, Q9NVJ5, Q9UJP1, |
| UniProt Related Accession: | Q8N126 |
| Molecular Weight: | 38,326 Da |
| NCBI Full Name: | Cell adhesion molecule 3 |
| NCBI Synonym Full Names: | cell adhesion molecule 3 |
| NCBI Official Symbol: | CADM3 |
| NCBI Official Synonym Symbols: | BIgR; NECL1; TSLL1; IGSF4B; Necl-1; synCAM3 |
| NCBI Protein Information: | cell adhesion molecule 3 |
| UniProt Protein Name: | Cell adhesion molecule 3 |
| UniProt Synonym Protein Names: | Brain immunoglobulin receptor; Immunoglobulin superfamily member 4B; IgSF4B; Nectin-like protein 1; NECL-1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like protein 1; TSLL1 |
| Protein Family: | Cell adhesion molecule |
| UniProt Gene Name: | CADM3 |
| UniProt Entry Name: | CADM3_HUMAN |
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