Name: Anti-CACNG4 Antibody (CAB7588)
Brand: Cell Biology Antibodies 11
SKU: CAB7588
Availability: OutOfStock

Antibody Name:	Anti-CACNG4 Antibody
Antibody SKU:	CAB7588
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 208-327 of human CACNG4 (NP_055220.1).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Mouse
Positive Samples:	Mouse brain

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 208-327 of human CACNG4 (NP_055220.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	EKNK ELRF KTKR EFLK ASSS SPYA RMPS YRYR RRRS RSSS RSTE ASPS RDVS PMGL KITG AIPM GELS MYTL SREP LKVT TAAS YSPD QEAS FLQV HDFF QQDL KEGF HVSM LNRR TTPV
Gene ID:	27092
Uniprot:	Q9UBN1
Cellular Location:	Cell membrane, Multi-pass membrane protein
Calculated MW:	36kDa
Observed MW:	40kDa

Synonyms:	CACNG4
Background:	The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit.

UniProt Protein Function:	CACNG4: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
UniProt Protein Details:	Protein type:Membrane protein, multi-pass; Membrane protein, integral; Channel, calcium Chromosomal Location of Human Ortholog: 17q24 Cellular Component: integral to plasma membrane; plasma membrane; voltage-gated calcium channel complex Molecular Function:channel regulator activity; voltage-gated calcium channel activity Biological Process: membrane depolarization; synaptic transmission; transmission of nerve impulse; transport
NCBI Summary:	The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010]
UniProt Code:	Q9UBN1
NCBI GenInfo Identifier:	10719940
NCBI Gene ID:	27092
NCBI Accession:	Q9UBN1.1
UniProt Secondary Accession:	Q9UBN1,B2RCK0,
UniProt Related Accession:	Q9UBN1
Molecular Weight:	36,579 Da
NCBI Full Name:	Voltage-dependent calcium channel gamma-4 subunit
NCBI Synonym Full Names:	calcium voltage-gated channel auxiliary subunit gamma 4
NCBI Official Symbol:	CACNG4
NCBI Protein Information:	voltage-dependent calcium channel gamma-4 subunit
UniProt Protein Name:	Voltage-dependent calcium channel gamma-4 subunit
UniProt Synonym Protein Names:	Neuronal voltage-gated calcium channel gamma-4 subunit; Transmembrane AMPAR regulatory protein gamma-4; TARP gamma-4
Protein Family:	Voltage-dependent calcium channel
UniProt Gene Name:	CACNG4
UniProt Entry Name:	CCG4_HUMAN

Western blot analysis of extracts of mouse brain, using CACNG4 antibody (CAB7588) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.

Antibodies

Anti-CACNG4 Antibody (CAB14118)

CACNG4 Antibody (PACO07024)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)